女性生殖道解脲支原体及人型支原体感染680例耐药性分析.docVIP

女性生殖道解脲支原体及人型支原体感染680例耐药性分析 　【摘要】 目的 了解本地区女性生殖道解脲支原体（Uu）及人型支原体（Mh）感染率及对不同药物的耐药情况。方法 采用女性子宫颈管分泌物培养+药敏法进行支原体感染及耐药性分析。结果 在680例女性患者中，Uu、Mh、Uu+Mh阳性率分别为60.59%，12.35%，6.91%；药敏试验结果显示：Uu对喹诺酮类药物环丙沙星、可乐必妥、司帕沙星的耐药率居10种抗菌药前列，耐药率分别为92.71%、32.52%、26.94%；Uu对交沙霉素、强力霉素、克拉霉素敏感，敏感率分别为95.36%、91.99%、87.86%；Mh则对环丙沙星、红霉素、罗红霉素的耐药率高，耐药率分别为91.67%、80.95%、80.95%；Mh对强力霉素、交沙霉素、克拉霉素较为敏感，敏感率分别为73.81%、70.24%和47.62%。结论 Uu对环丙沙星、可乐必妥、司帕沙星的耐药率高，Mh则对环丙沙星、红霉素、罗红霉素耐药率高，Uu和Mh均对交沙霉素和强力霉素敏感，可作为治疗支原体感染的首选抗生素和经验用药。 【关键词】 支原体；药物耐药性；生殖道 Analysis on 680 cases of female infection and drug sensitivity test of ureaplasma urealyticum and mycoplasma hominis ［Abstract］ Objective To find out the infection percentage of local feminine ureaplasma urealyticum（Uu）and mycoplasma hominis（Mh）and the antibiotics resistance of different drugs.Methods We used the feminine endocervical secretions raise and medicine sensitive method to carry on the analysis of the mycoplasma infection and the antibiotics resistance.Results Among the 680 feminine patients,positive rate of Uu was 60.59%,of Mh was 12.35%,of Uu and Mh was 6.91%;The result of Medicine sensitive experimentation was that the Uu?s antibiotics resistance of quinolone compounds such as ciprofloxacin,cravit tablets and sparfloxacin was the first of ten kinds of antibacterial medicines,antibiotics resistance rate of ciprofloxacin was 92.71%,of cravit tablets in 32.52%,of sparfloxacin was 26.94%,Uu was sensitive to josamycin,doxycycline and clarithromycin,sensitive rate of josamycin was 95.36%,of doxycycline was 91.99%,of clarithromycin was 87.86%,Mh?s antibiotics resistance of ciprofloxacin,erythromycin and roxithromycin was high,antibiotics resistance rate of ciprofloxacin was 91.67%,of erythromycin was 80.95%,of roxithromycin was 80.95%,Mh was sensitive to doxycycline,josamycin and clarithromycin,sensitive rate of doxycycline was 73.81%,of josamycin was 70.24%,of clarithromycin was 47.62%.Conclusion Uu?s antibiotics resistance of ciprofloxacin,cravittablets and sparfloxaci