羊栖菜提取物的降血糖作用研究（Study on the hypoglycemic effect of the extract of Sargassum fusiforme）.doc

羊栖菜提取物的降血糖作用研究（Study on the hypoglycemic effect of the extract of Sargassum fusiforme） Study on the hypoglycemic effect of the extract of Sargassum fusiforme Update Date: 06-07 [keyword] sheep habitat Abstract: Objective To study the effect of Sargassum fusiforme extract on normal and alloxan induced diabetic mice four glucose. Methods four alloxan diabetic mice model with blood glucose and glucose tolerance for the hypoglycemic effect of Sargassum extract index. The results of the extract of Sargassum fusiforme on normal mice without hypoglycemic effect; prophylactic administration of Sargassum fusiforme polysaccharide (350700 mg? Kg1), four blood glucose in alloxan diabetic mice was significantly decreased; SFPs and ethanol extracts (700 mg? Kg1) have therapeutic effects, can significantly reduce the blood glucose level of diabetic mice to normal; mice and diabetic mice without significant improvement in glucose tolerance. Conclusion Sargassum extract can prevent and cure four in alloxan diabetic mice. Keywords: Sargassum extract; alloxan; four; blood glucose Study, on, the, Hypoglycemic, Effect, of, the, Extract,, of, Sargassum, fusiforme Abstract:ObjectiveTo explore the effect of the extract of Sargassum fusiforme (ESF) on blood glucose in diabetes mice. MethodsEffect of ESF on alloxan-inducing diabetes mellitus model was investigated by blood glucose concentration and glucose tolerance test. ResultsESF can t decrease the blood sugar level in normal mice. At doses of 350 and 700 mg/kg, SFP (Sargassum fusiforme polysaccharide) has prophylactic effect in diabetic mice. At dose of 700 mg/kg ESF reduces, the blood glucose level significantly. Besides there no marked changes of the re glucose tolerance in normal or diabetes mellitus mice. ConclusionThe results show that ESF are active components in protecting against alloxaninduced pancreas injury and mediating the blo Od glucose level. Key, words:Sargassum, fusiforme; Extract; Alloxan; glucose; Blood From Sargassum