药学-酪蛋白磷酸肽的药理作用(Pharmacological effects of casein casein phosphopeptides).docVIP

药学-酪蛋白磷酸肽的药理作用(Pharmacological effects of casein casein phosphopeptides).doc

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药学-酪蛋白磷酸肽的药理作用(Pharmacological effects of casein casein phosphopeptides)

药学-酪蛋白磷酸肽的药理作用(Pharmacological effects of casein casein phosphopeptides) Casein phosphopeptides can promote the absorption and utilization of calcium, iron and zinc, and enhance the binding of sperm and eggs. In recent years, the study found it to enhance immunity, a potential pharmacological action promoting apoptosis of tumor cells, through the study on its mechanism of action, will provide a theoretical basis for its clinical use. The Keywords casein phosphopeptides; pharmacological effects; [Abstract] Casein protein phosphorylation peptide with the promotion of calcium, iron, zinc absorption, utilization and enhance the integration of sperm, In recent years their has conducted in-depth study found that it enhanced immunity, and promote apoptosis of tumor cells have the potential pharmacological effects, through the mechanism of its role will be to provide a theoretical the basis for clinical. [Key, words] Casein, Phospho, peptides, Pharmacological, effects English: Casein Phospho Peptides (CPP) Alias: the casein phosphopeptides The chemical structure of the active site of CPP is: clusters of phosphoserine and glutamate group, its basic structure can be expressed as -serp-serp-serp-glu-glu-, the relative molecular mass of about 2000~4000. The Description: creamy white or yellowish powder with a slight aromatic odor. Soluble in water, water solution is neutral, in acid conditions are not easy to precipitate. Good thermal stability. The Source and structure: Nato[1] was the first to feed rats with casein, and CPP was found in the gut contents. Nicholas and so on [2-3] hydrolyzed casein with trypsin or trypsin, purified and purified to prepare CCP. CPPs alpha and beta two configurations of [4], its main function is SI- (59-79) 5P alpha and beta (1-25) 4P, prepared under different conditions CPP have the same core structure: -Ser (P) -Ser (P) -Ser (P) -Glu-Glu- (Ser: Glu: P: serine, glutamic acid, phosphoric acid base). In this structure, the serine residue [-Ser (P

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