药物效价与重量换算（Drug titer and weight conversion）.docVIP

药物效价与重量换算（Drug titer and weight conversion） Drug potency unit conversion What is biological potency unit? A unit of measurement for the pharmacokinetics of drugs, usually the amount of effective units, we have the smallest effective amount as a unit of measurement, there is a valence said. The drugs commonly used in clinic are biological agents, hormones, vitamins and some antibiotics. These drugs, according to the Chinese Pharmacopoeia, are marked by their unique pharmacological potency. Most antibiotics use a certain weight of their active part (1 g) as the 1 unit. Such as streptomycin, oxytetracycline, erythromycin and so on, YISHION free alkali 1 mu g or a certain weight as the 1 unit. It is worth noting that, in the development of the pharmaceutical industry, with the improvement of pharmaceutical technology, the purity of the drug has increased year by year, and its biological value is also getting higher and higher. Such as heparin mentioned above, the development of early drug bioavailability, each 1.0mg titer is equivalent to 125U, China Pharmacopoeia 1977 provisions of heparin sodium per 1.0mg was less than 140U, while the Chinese Pharmacopoeia 1995 edition is scheduled for each 1.0mg was not less than 150U, the current clinical 12500U/ heparin sodium as a branch of 100mg/, is still the initial biological potency of heparin sodium standard as the basis. If the 1995 edition of the pharmacopoeia is equivalent to the 150U of heparin sodium 1.0mg, the 12500U/ branch should be equivalent to the 83.3mg rather than the 100mg/ branch. Therefore, the potency of the same drug is not exactly the same as the dose of the drug itself, and even the dosage conversion between each other has no equal substitution relationship. The general drug weight in gram as the basic unit, the capacity is the basic unit in ml. Such as 1g=1000mg, 1L=1000ml, these units of measurement and conversion relation is very intuitive, but some drugs, such as biological agents and antibiotics due