阿苯达唑百科名片（Albendazole）.docVIP

阿苯达唑百科名片（Albendazole） Albendazole Albendazole is an efficient, low toxic broad-spectrum anthelmintic. Can be used for clinical roundworm, pinworm and tapeworm, hookworm, Trichuris, fecal nematodes etc.. In vivo metabolism to sulfoxides or sulfones, inhibit the absorption of glucose in insect parasites, glycogen depletion or inhibition of fumarate reductase system, hinder the generation of ATP, the parasite can not survive and reproduce. Catalog Basic data Drug properties pharmacology and toxicology Scope of application usage and dosage Matters needing attention Pharmacokinetics Edit the basic data of this paragraph Alias: rosickyite albendazole, albendazole, albendazole, albendazole zentel, ZENTEL, A, albendazole molecular formula BENTEL English Name: Albendazole English alias: Methyl5-propylthio-2-benzimidazolecarbamate CASNO:54965-21-8 molecular formula: C12H15N3O2S, albendazole, molecular formula, molecular weight: 265.33 Edit this section of drug properties Albendazole is a white or white powder, odorless, tasteless, insoluble in water, slightly soluble in acetone or chloroform. Edit this section of pharmacology and Toxicology Benzimidazole derivatives are rapidly metabolized to sulfoxide, sulfone alcohol and 2- amine sulfone in vivo. Albendazole The polymerization of intestinal nematode selective and irreversible inhibition of intestinal parasite cytoplasmic microtubule system, blocking the variety of nutrients and glucose uptake and absorption, causes polypite endogenous glycogen depletion, and inhibition of fumarate reductase system, prevent ATP generation, causing worms to survive and multiply. Similar with mebendazole, this product can also cause polypite intestines cytoplasm degeneration of microtubules and tubulin binding, intracellular transport congestion, resulting in the accumulation of secretory granules Golgi, cytoplasm gradually dissolved absorption cells completely denatured, caused by the parasite. This product is completely kill whipworm eggs an