皮肤性病学笔记（Dermatology notes）.doc

皮肤性病学笔记（Dermatology notes） The main manifestations of neonatal gonorrhea (1) neonatal gonococcal conjunctivitis: conjunctival edema, congestion, purulent secretions (2), other: bacteremia, arthritis, swelling of the scalp, anus, genitals, nasopharynx Condyloma acuminata: pathogenic bacteria: human papilloma virus Simple discussion: The epidermis is divided into basal layer, spinous layer, granular layer, transparent layer and stratum corneum from inside to outside under the light microscope. Basal layer: melanin granules, mainly distributed above the nucleus. 2. spinous layer: there are generally 4-10 layers of polygonal cells, and the intercellular bridge is obviously spinous. 3. granular layer: characterized by the presence of irregular basophilic basophilic horny granules in the cell. 4. transparent layer: restricted palmoplantar. 5. stratum corneum: composed of dead cells. 6. the connection between keratinocytes and the basement membrane zone: desmosomes are the primary structures of the intercellular junction of keratinocytes. Desmosomes are composed of transmembrane proteins and intracytoplasmic plaques. Skin appendages: 1. hair: divided into three layers: the central medulla is located in hair, 2~3 layer shrinkage cubic keratinocyte line. The cortex is the main body of hair, is composed of several layers of prismatic keratinocytes, cell containing a large number of pigment granules; the Mao Xiaopi hair surface with a thin and transparent keratinized cells, such as imbricate overlap. 2. hair follicles: the upper part consists of funnel and isthmus, and the lower section consists of stem and bulb. 3. sebaceous glands. 4. small sweat glands: there are two types of secretory cells: clear cells and dark cells. They are clear cells, narrow at the top and wide at the bottom. They are the main cells that secrete sweat glands. The dark cells are small, sandwiched between the clear cells, wide at the top and narrow at the bottom. 5. apocrine sweat glands: composed of s