纳多洛尔（Naidoo Carol）.docVIP

纳多洛尔（Naidoo Carol） Naidoo Carol [name of drug] Naidoo Carol English Name: Nadolol Other name: nadolol, nadolol, nadolol, corgard, nadolol, hydroxy propranolol, nadolol, Anabet, Apo-Nadol, Corgard, Nadololum, Solgol [clinical application] 1. for high blood pressure, angina pectoris. * (1) the treatment of hypertension can be used alone or combined with other drugs. * (2). 2. also for arrhythmia, myocardial infarction (1). * (foreign materials), * (2) * * hyperthyroidism, migraine (1) and tremor (the foreign data reports). * (2). [pharmacology] 1. pharmacodynamics is a nonselective beta adrenergic receptor blocker, without membrane stabilization and endogenous quasi sympathetic activity (ISA), with low fat solubility. * (2) this medicine. 1. Through competition beta and beta 2 * * receptor binding sites, antagonize sympathetic neurotransmitters, can cause cardiac contractility, heart rate, cardiac output decreased, decreased blood pressure and plasma renin activity decreased. The effect was similar to that of propranolol, but 2-4 times stronger than that of propranolol. (1) the effect characteristics of heart rate, myocardial significantly weaker inhibition and can increase renal blood flow. * (3). A large number of studies show that the long-term treatment of angina pectoris (effective drugs can reduce the dosage of nitroglycerin, reduce angina attack frequency and severity, increasing exercise intensity and duration), treatment of grade I and II (mild to moderate hypertension effectively). The drug is reported to be effective in controlling tachycardia associated with hyperthyroidism, palpitations, neuroticism, hyperactivity, and finger tremors. However, the effectiveness of this drug in the treatment of hyperthyroidism, migraine prevention, and the treatment of tremor has not been determined. * (2). Mechanisms of action (1) antihypertensive: this drug is associated with reduced cardiac output (negative inotropic and negative frequency effects), decreased epinephrin