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测定女性性激素六项的临床意义(Clinical significance of six items of female sex hormones)
测定女性性激素六项的临床意义(Clinical significance of six items of female sex hormones)
With the female lifetime gonadal axis is the hypothalamic pituitary ovarian axis (HPOA), its main function is to control the female normal menstruation and sexual function, development, this function is mediated by neural regulation and hormone feedback regulation completed. Therefore, the endocrine function of female and the diagnosis of endocrine disorder are determined by measuring the level of sex hormone in clinic. The six sex hormones that follicle stimulating hormone (FSH) and luteinizing hormone (LH), estradiol (E2) and progesterone (P), testosterone (T), prolactin (PRL), basically meet the needs of clinicians on endocrine disorders or screening and physiological function of the general solution.
Menstruation is an important physiological link in womens life. It reflects the process of functional development, maturation and decline of HPOA axis. Normal menstruation and periodic changes are regulated by periodic changes in the ovary, i.e., follicular phase: FSH and LH are maintained at a low level, and E gradually increases with follicular development, and P is only trace. Ovulation: ovulation 24 hours before, FSH is low peak secretion, LH is steep peak secretion, E than FSH and LH appear slightly earlier, is also peak secretion, in ovulation, FSH and LH plummeted. Luteal phase: FSH and LH remained at low levels, and E and P increased with the development of corpus luteum, and reached the highest 7E8 in Tianda after ovulation.
Menstrual cramps before the FSH, LH, E, P were decreased to the lowest value, gradually return to continue to the next cycle after menstruation. When women entered perimenopausal period, HPOA function showed progressive decline, E secretion gradually decreased to disappearance, T secretion, and secretion of FSH and LH gradually increased, and FSH, /LH1.
1 Determination of gonadotropin (FSH, LH)
1.1 the cause of amenorrhea is that the level of FSH and LH is lower t
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