加味大柴胡汤对阻塞性黄疸大鼠中胆红素主要转运子地表达和肝脏能量代谢改变地影响.pdfVIP

after TBAcontentsweretOlast inBDL+MMDBandBDL+NS BDL，serum upgrade is toSO group．Itoppositegroup(P0．05)． of inliver 2．ExpressionMRP2 protein MRP2 localizes tothe membraneand protein exclusivelyapical cytoplasm， whichis ata levelinnormallivercells．Onthe high 7”，14“， constitutivelyexpressed afterBDL MRP2 were of SO others 21“day expressionsproteingroup normal，the were whichBDL+NSwerelowerthanBDL+MMDB continuelyweaken，in group instatisticsbetweenBDL+MMDBandSOwere group(P0．01)．Comparison highly significant(P0．01)． of mRNAinliver MRP2 3．Expression 0nthe afterBDL ofMRP2mRNASO were 7”，14…，21。‘day expressions group otherswere whichBDL+NS than normal，the continuelyweaken，in werelower group BDL+MMDB instatisticsbetweenBDL+MMDBand group(P0．01)．Comparison SOwere highlysignificantfPO．01)． of inliver ATP，EC 4．assaying On the afterBDL ofATP．ECinliverinBDL+NS 7”day assaying group declinedwithtimeextension．therewerenodifferenceinstatistics gradually along betweenBDL+MMDB the andSO timeBDL+MMDB group group(PO．05)，on BDL+NSwere in