液相色谱-串联质谱法测定饮用水中的卤氧化物.PDF

8 2 Vol. 8 No. 2 2017 2 Journal of Food Safety and Quality Feb. , 2017 - * 余婷婷 , 张 莉, 万旭刚, 王会霞, 朱晓玲, 范志勇 ( , 432700) 摘 要: 目的 -(liquid chromatography-tandem mass spectrometry, LC-MS/MS) 3 ()方法 0.22 μm , 100 mmol/L (A)(B), IC-PakTM Anion HR , (ESI-)(MRM) 3 结果 6 min 3 0.5~50 μg/L 0.5~100 μg/L (r 0.999)0.510.050.0 μg/L, 84.8%~101.4%, 10.0% (n=6) μg/L结论 , 关键词: -; ; ; ; Determination of oxyhalides in drinking water by liquid chromatography-tandem mass spectrometry * YU Ting-Ting , ZHANG Li, WAN Xu-Gang, WANG Hui-Xia, ZHU Xiao-Ling, FAN Zhi-Rong (Hubei Provincial Institute for Food Supervision and Test, Wuhan 432700, China) ABSTRACT: Objective To establish a method for the simultaneous determination of 3 kinds of oxyhalides (perchlorate, chlorate and bromate) in drinking water by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Methods Water samples were directly filtered with 0.22 μm hydrophilic filter membrane, and then the 3 kinds of oxyhalides in the water samples were separated on an IC-PakTM Anion HR column using an isocratic elution program of 100 mmol/L ammonium acetate solution (A) and acetonitrile (B). Using LC-MS/MS (ESI-) with multiple reactions monitoring (MRM), identification of