射频消融过程中肝组织热传导效应的模拟实验研究.PDFVIP

Med J Chin PLA, Vol. 38, No. 5, May 1, 2013 351 (RFA)(HCE) 70 10min5mm 10mm80~90 80 40min (55 ) 90 25min 80~90 25~40min 10mm55 R735.7 A 0577-7402(2013)05-0351-04 Simulation research of “heat conduction effect” of liver tissue during radiofrequency ablation * JIANG Kai, SU Ming, LIU Yang, ZHAO Xiang-qian, ZHANG Wen-zhi, WANG Jing, DONG Jia-hong , HUANG Zhi-qiang Department of Hepatobiliary Surgery, General Hospital of PLA, Beijing 100853, China * Corresponding author, E-mail:dongjh301@163.com This work was supported by the National Key Technology Research and Development Program of China (2012BAI06B01) [Abstract]Objective To explore the heat conduction effect (HCE) and effective extent in liver tissue produced by radiofrequency ablation (RFA). MethodsTo simulate the HCE produced by RFA, isolated swine livers were heated to different temperature for a range of different heating time with RFA. The temperature of liver in different distance away from the center and the changes in color and morphology of liver tissue after radiofrequency treatment were recorded to explore the attenuation pattern of different heating center temperature and duration of treatment. ResultsWhen the temperature of heating center reached 70 , 5mm in radius of liver tissue was ablated in 10min. To expand the range to 10mm, central temperature should be maintained above 80 or 90 , and the heating time should be maintained for 40min and 25min, respectively. ConclusionTo complete ablation of an area of liver tissue with 10mm in diameter with HCE, the temperature of heating center should be maintained at higher than 80- 90 and the ablation time should be main