皮层脑电图在单发性海绵状血管瘤手术中的运用-中南大学学报医学版.pdfVIP

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皮层脑电图在单发性海绵状血管瘤手术中的运用-中南大学学报医学版.pdf

皮层脑电图在单发性海绵状血管瘤手术中的运用-中南大学学报医学版

中南大学学报(医学版)  2008,33(5) 448 JCentSouthUniv(MedSci) 皮层脑电图在单发性海绵状血管瘤手术中的运用 霍雷,吴雷,张明宇,侯永宏,丁锡平,方加胜 (中南大学湘雅医院神经外科,长沙410008) [摘要]  目的:探讨术中应用皮层脑电图(ECoG)监测对提高有癫痫史的海绵状血管瘤手术疗效的 作用。方法:对 ECoG监测下显微手术治疗的71例有癫痫病史的单发性海绵状血管瘤病例的临床资料 进行回顾性分析。结果:71例患者均在 ECoG监测下行显微手术,切除病灶及局部癫痫灶;随访 58例, 其中42例无癫痫发作,13例发作减少90%以上,3例效果不佳。结论:海绵状血管瘤伴有癫痫发作者 药物治疗效果不佳,应早期行外科手术治疗。术中ECoG监测对指导手术切除癫痫灶,减少术后癫痫的 发作有较大帮助。 [关键词]  海绵状血管瘤; 癫痫; 手术; 皮层脑电图 [中图分类号] R741.044 [文献标识码] A [文章编号] 16727347(2008)05044804 Electrocorticographymonitoringinmicrosurgicaltreatment ofsolitarycavernousangiomas HUOLei,WULei,ZHANGMingyu,HOUYonghong,DINGXiping,FANGJiasheng (DepartmentofNeurosurgery,XiangyaHospital,CentralSouthUniversity,Changsha410008,China) Abstract: Objective Toinvestigatethecurativeeffectofelectrocorticography(ECoG)moni toringinthemicrosurgicaltreatmentofcavernousangiomas.Methods Clinicaldataof71patients withepileptogeniccavernousangiomas,whohadbeenperformedECoGmonitoringduringtheopera tion,wereanalyzedretrospectively.Results Thefociofcavernousangiomasandepilepsyofthe71 patientswereresectedduringtheoperation.Inthe58patientswhowerefollowedup,42hadnotepi lepticseizure,and16stillhadepilepticseizure,whilethefrequenciesof13patientsreducedtobelow 10%,and3patientsover10%.Conclusion Thedrugtreatmentofepileptogeniccavernousangio mascannotcontrolepilepticseizure,andthepatientsshouldreceivethemicrosurgicaltreatmentear ly.Electrocorticographymonitoringcandirectthesurgicalprocedure,andcontrolthepostoperative epilepticseizure. Keywords: cavernousangiomas; epilepsy; operation; electrocorticography [JCentSouthUniv(Me

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