超声用于RA低疾病活动时复发或影像学进展预测2012.pdfVIP

ARTHRITIS RHEUMATISM Vol. 64, No. 1, January 2012, pp 67–76 DOI 10.1002/art.33312 © 2012 American College of Rheumatology Power Doppler Ultrasound, but Not Low-Field Magnetic Resonance Imaging, Predicts Relapse and Radiographic Disease Progression in Rheumatoid Arthritis Patients With Low Levels of Disease Activity Violaine Foltz,1 1 1 1 Fre´de´rique Gandjbakhch, Fabien Etchepare, Carole Rosenberg, Marie Laure Tanguy,2 Sylvie Rozenberg,1 Pierre Bourgeois,1 and Bruno Fautrel1 Objective. Subclinical inflammation and radio- disease duration of 35.3 months were studied. RA was in graphic progression have been described in rheumatoid remission in 47 of these patients, and 38 had low levels arthritis (RA) patients whose disease is in remission or of disease activity. At 1 year, 26 of the 85 patients is showing a low level of activity. The aim of this study (30.6%) showed disease relapse, and 9 of the 85 patients was to compare the ability of ultrasonography and (10.6%) showed radiographic progression. The baseline magnetic resonance imaging (MRI) to predict relapse PD synovitis count (i.e., the number of joints at baseline and radiographic progression in these patients. for which the power Doppler [PD] signal indicated Methods. Patients with RA of short or intermedi- synovitis) predicted relapse (adjusted odds ratio [OR] ate duration that was either in remission or exhibiting 6.3; 95% confidence interval [95% CI] 2.0–20.3), and the low levels of activity according to the Disease Activity basel