味地黄丸.pptVIP

六 味 地 黄 丸 Liuweidihuangwan Ingredients——处方 Procedure——制法 Description——性状 Identification——鉴别 Other requirements——检查 Assay——含量测定 Action——功能 Indication——主治 Usage and dosage——用法与用量 Specification——规格 Storage——贮藏 熟 地黄 160g 山茱萸 80g 处方 （成分） 牡丹皮 60 g 山 药 80g 茯苓 60 g 泽泻 60 g pulverize: 研磨 sift：评审，过筛 Procedure/制法 以上六味，粉碎成细粉，过筛，混匀。每100g粉末加炼蜜35~50g与适量的水，泛丸，干燥，制成水蜜丸；或加炼蜜80~110g制成小蜜丸或大蜜丸，即得。 make pills : 泛丸 Description 本品为棕黑色的水蜜丸、黑褐色的小蜜丸或大蜜丸；味甜而酸。 Identification Microscopical Starch granules triangular-ovoid or oblong, 24～40μm in diameter, hila short cleft or V-shaped. Irregular branched masses color less, dissolved in chloral hydrate solution: hyphae colorless, 4～6μm in diameter. cleft：裂缝 hyphae：菌丝 chloral hydrate solution 水合氯醛溶液 Epidermal cells of pericarp orange-yellow, polygonal in surface view, with somewhat beaded anticlinal walls. epidermal: 表皮的 pericarp: 果皮 beaded anticlinal walls:垂周壁念珠状增厚 anticlinal walls of the endodermis cells sinuous, thickened, lignified, with slender pit-canals. 内皮层细胞垂周壁波状弯曲，较厚，木化，有细长孔沟。 Pulverize 6 g of the water-honeyed pills, or triturate 9 g of the small honeyed pills or big honeyed pills with 4 g of kieselguhr and triturate well. Heat under reflux with 40 ml of ether at a low temperature for 1 hour, cool , filter and evaporate to remove ether. kieselguhr: 硅藻土 triturate: 研匀 Physical and Chemical identification paeonol: 丹皮酚 cyclohexane: 环己烷 ferric chloride：三氯化铁 hydrochloric acid ：盐酸 5% ferric chloride in ethanol acidified with hydrochloric acid 盐酸酸化的5%三氯化铁乙醇溶液 供试品色谱中，在与对照品色谱相应的位置上显相同的蓝褐色斑点。 Assay 含量测定 octadecylsilane bonded silica gel 十八烷基键合硅胶 Tetrahydrofuran 四氢呋喃 acetonitrile 乙腈 stopper conical flask 具塞锥形瓶 Ultrasonicate 超声（提取） heat under reflux 加热回流 replenish the lost weight with / 补重 the successive filtrate：续滤液 neutral aluminium oxide：中性氧化铝 elute ：洗脱 eluate：洗脱液 volumetric flask：容量瓶 dilute with 50% methanol to volume：定容 Procedure: 测定法 山茱萸 牡丹