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Clinical Expert Series 
Abnormal Placentation 
Placenta Previa, Vasa Previa, and Placenta Accreta 
Robert M. Silver, MD 
             Placental disorders such as placenta previa, placenta accreta, and vasa previa are all associated 
             with vaginal bleeding in the second half of pregnancy. They are also important causes of serious 
             fetal and maternal morbidity and even mortality. Moreover, the rates of previa and accreta are 
             increasing,   probably  as  a  result  of  increasing    rates  of  cesarean  delivery,  maternal     age,  and 
             assisted   reproductive     technology.    The  routine   use   of  obstetric   ultrasonography     as  well  as 
             improving ultrasonographic technology allows for the antenatal diagnosis of these conditions. In 
             turn, antenatal diagnosis facilitates optimal obstetric management. This review emphasizes an 
             evidence-based approach to the clinical management of pregnancies with these conditions as 
             well as highlights important knowledge gaps. 
              (Obstet Gynecol 2015;126:654–68) 
              DOI: 10.1097/AOG.0000000000001005 
PLACENTA PREVIA                                                         (eg,  3.2  cm  over  the  os  or  1.3  cm  away  from  the 
Background                                                              os) should be reported for low-lying placentas. 
                                                                             The    incidence     is  estimated     to   be   1   in    200 
Placenta  previa  is  defined  as  the  placenta  overlying 
the   endocervical       os.  In   the   past,    previas    were       pregnancies      at   term    and    varies    throughout      the 
characterized      as   complete,     partial,   and    marginal        world.2,3   The incidence appears to have increased in 
depending on how much of the internal endocervical                      relationship to th
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