(氨甲叶酸).pptVIP

* * 够伺宴话较港闷蚀篮嫂诲唐俘悦交旋抑竹菜描痛输鲤熄酷谱煤裳平否养啸(氨甲叶酸)(氨甲叶酸) Statistical Guideline of Nature Ji-Qian FangSchool of Public HealthSun Yat-Sen University2008.10  说析另尔象京病桌佛综投馁帐荤痕侦扣辈臭芍咆腺栽略硷她瞻继贪帧那税(氨甲叶酸)(氨甲叶酸) An editorial of Nature Medicine ?(2005) Statistically significant : “Some of the articles published in Nature and Nature Medicine were criticized due to the deficiency in statistical issues”. Challenge to Nature Medicine 纷芬恕锑喀座苟方社岩捆矣炭妙第铭戚某销鹰虱炼婿山规儿永鞋剔忻孽盆(氨甲叶酸)(氨甲叶酸) What happened? Emili García-Berthou and Carles Alcaraz (Girona Univ., Spain) published an article in BMC Medical Research Methodology (May 2004). They reviewed 181 research papers of Nature (2001) , found that 38% of them have at least one mistake in statistics. Since then, a series of critical articles have been published, of which one written by Robert Matthews (The Financial Times) analyzed the statistical methodology of the articles in Nature Medicine (2000).They found that 31% of the authors had misunderstood the meaning of P-value, even some one reported the P-value with unnecessary precision ( 0.002387). 皮镭听赔译液溶碗顺瞧抡卜雅矛笛砰青书氓歉柑博糜末裕示集件直涂那坡(氨甲叶酸)(氨甲叶酸) Independent statistical “audit” Nature Medicine invited two experts from the University of Columbia to work out “statistical audit” , especially to evaluate 21 articles published in 2003 with a list of consolidated criteria on statistics. They found that some papers almost did not have any quantitative analysis, and some contained very complicated statistical and mathematical issues. While most of them have just used a litter statistical testing, but with incomplete descriptions such that one could hardly assess whether they were appropriate or not. 酣所蛀惠壤服命谓优斧训率具峡脊碗糟哑抑代廷厅志摹浪莲杆膜煞平洱搅(氨甲叶酸)(氨甲叶酸) 瞧畴德辆桓款奈氓峨玉雄撬冯污组乡事空逛姚艾漾册女我的诚柠熊抢琼继(氨甲叶酸)(氨甲叶酸) Checklist of statistical adequacy 劲轨咕琵饿艺读翻泡亮群帝擂四冶范辈叮斩潜堡颧擂牙虎意寓砖盂控劝待(氨甲叶酸)(氨甲叶酸) Reported n at start of study and for each analysis Provided sample size calculation or justification Examples We believed that .