MR医学影像文献Lu-2016-A novel method for assessing signal in.pdfVIP

Osteoarthritis and Cartilage 24 (2016) 1883e1889 A novel method for assessing signal intensity within infrapatellar fat pad on MR images in patients with knee osteoarthritis M. Lu y z x a, Z. Chen y k a, W. Han y, Z. Zhu y x, X. Jin y, D.J. Hunter ¶, C. Ding y x ¶ * y Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia z Department of Orthopaedics, 1st Affi liated Hospital, Anhui Medical University, Hefei, Anhui, China x Arthritis Research Institute, 1st Affi liated Hospital, Anhui Medical University, Hefei, Anhui, China k School of Engineering, Southeast University, Nanjing, China ¶ Institute of Bone and Joint Research, Kolling Institute, University of Sydney; Rheumatology Department, Royal North Shore Hospital, Sydney, NSW, Australia a r t i c l e i n f o s u m m a r y Article history: Purpose: To assess reliability and validity of a semi-automated quantitative method to measure infra- Received 8 November 2015 patellar fat pad (IPFP) signal intensity in patients with knee osteoarthritis (OA). Accepted 11 June 2016 Methods: Hundred patients with knee OA were selected. Sagittal planes of fat-saturated T2-weighted images obtained on 1.5-T magnetic resonance imaging (MRI) were utilized to assess IPFP signal in- Keywords: tensity using MATLAB. Knee structural abnormalities including cartilage defects, bone marrow lesions Osteoarthritis (BML) and radiographic OA (ROA) were evaluated. Infrapatellar fat pad Clinical construct validi