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Computers in Biology and Medicine 76 (2016) 69–79
Contents lists available at ScienceDirect
Computers in Biology and Medicine
journal homepage: /locate/cbm
Local structure orientation descriptor based on intra-image similarity
for multimodal registration of liver ultrasound and MR images
Minglei Yang a, Hui Ding a, Jingang Kang b, Longfei Cong b, Lei Zhu b, Guangzhi Wang a,n
a Department of Biomedical Engineering, School of Medicine, Tsinghua University, Room C249, Beijing 100084, China
b Beijing Shen Mindray Medical Electronics Technology Research Institute Co. Ltd, 3 F, Building5, No.8 Chuangye Road, Shangdi Haidian District, Beijing
100085, China
a r t i c l e i n f o a b s t r a c t
Article history: Purpose: Ultrasound (US)-magnetic resonance (MR) fusion imaging is a profitable tool for image-guided
Received 21 April 2016 abdominal diagnosis and biopsy. However, the automatic registration of liver US and MR images remains
Received in revised form a challenging task. An effective local structure orientation descriptor (LSOD) for use in registering
11 June 2016 multimodal images is proposed in this study.
Accepted 24 June 2016
Methods: LSOD utilizes a normalized similarity distance vector of intra-image patch pairs to extract
intensity change orientations from intensity value changes in a local area. The multimodal similarity
Keywords: measure is then derived usi
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