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ONCOLOGY LETTERS 11: 4255-4263, 2016
Intravenous leiomyomatosis with intracardiac extension depicted
on computed tomography and magnetic resonance imaging
scans: A report of two cases and a review of the literature
HANJIANG ZENG, ZHONGZI XU, LIZHI ZHANG, YI LUO, HUI CHEN,
HONGJI ZHU, LIQING PENG and JIANQUN YU
Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
Received February 4, 2015; Accepted March 15, 2016
DOI: 10.3892/ol.2016.4499
Abstract. Intravenous leiomyomatosis (IVL) is defined as a the condition may be misdiagnosed as a primary cardiac
benign smooth muscle tumor, growing within systemic veins. tumor or a venous thrombus, which may lead to potentially
IVL with intracaval and intracardiac extension has rarely been life threatening consequences. Hence, early and accurate
reported in radiological and oncological journals. The present diagnosis and appropriate treatment choices are important for
study describes 2 cases of IVL extending from the inferior vena the patient prognosis. Complete surgical resection (single or
cava to the right atrium and ventricle, and discusses the imaging staged procedures) is the treatment option for IVL, as it is key
findings and differential diagnosis of this tumor entity. The two to preventing recurrence (3). The present study reports 2 cases
patients, who complained of palpitations, shortness of breath of IVL that were diagnosed using dual-source computed
or syncope, were surgically treated, with complete resection tomography (CT) and
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