中药提取分离新技术的研究进展-天津中草药杂志社.pdfVIP

中草药 Chinese Traditional and Herbal Drugs 第 46 卷 第 3 期 2015 年 2 月 ·457 · 中药提取分离新技术的研究进展 1, 2 1 2 1* 叶陈丽 ，贺 帅 ，曹伟灵 ，张忠义 1. 南方医科大学珠江医院 药剂科，广东 广州 510280 2. 深圳市罗湖区人民医院 药学部，广东 深圳 518001 摘 要：系统综述了近年来中药有效成分提取分离新技术，包括超高压提取、超声提取、微波萃取、加压溶剂提取、组织破 碎提取、免加热提取、高速逆流色谱分离技术、分子印迹技术。主要介绍了这些提取方法的基本原理、特点、应用进展、存 在的问题以及未来发展的方向等，以期为我国现代中药制药的研究和生产提供参考。 关键词：中药；提取技术；超高压提取；高速逆流色谱；分子印迹技术 中图分类号：R284.2 文献标志码：A 文章编号：0253 - 2670(2015)03 - 0457 - 08 DOI: 10.7501/j.issn.0253-2670.2015.03.028 Research progress in new technologies for extraction and separation of Chinese materia medica 1, 2 1 2 1 YE Chen-li , HE Shuai , CAO Wei-ling , ZHANG Zhong-yi 1. Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China 2. Department of Pharmacy, Shenzhen Luohu People’s Hospital, Shenzhen 518001, China Abstract: Extraction and separation technologies appeared in recent years are particularly reviewed in the principles, features, latest research and application results, and existing problems as well. These new techniques include ultrahigh pressure extraction (UPE), ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), pressurized solvent extraction (PSE), smashing tissue extraction (STE), heating-free extraction (HFE), high-speed countercurrent chromatography (HSCCC), and molecular imprinting technique (MIT). Further research topics and application prospects of these extraction and separation technologies are also suggested, so as to provide the reference for the research and production of modern Chinese materia medica. Key words: Chinese materia medica; extraction technology; ultrahigh pressure extraction; high-speed countercurrent chromatography; molecular imprinting technique 中药制药过程一般包括提取、分离、浓缩、干