小儿细菌性肺炎的病原菌及其耐药性分析郭燕峰浙江台州玉环.DOCVIP

小儿细菌性肺炎的病原菌及其耐药性分析 郭燕峰 浙江省台州市玉环县人民医院检验科317600 【作者简介】：郭燕峰（1979年），女，中级，玉环，大学本科，研究方向：微生物 ，通讯地址：浙江省台州市玉环县人民医院检验科。邮箱 【摘要】目的：探讨小儿细菌性肺炎的病原菌及其耐药性。方法：选择2010年1月1日-2012年12月31日我院儿科二病区2382例确诊为细菌性肺炎患儿痰培养标本，分析其感染病原菌的分布及耐药性情况。结果：小儿细菌性肺炎病原菌以革兰氏阴性菌为主，共477株，占比83.45%，其中肺炎克雷伯菌26.44%，大肠埃希菌25.22%，鲍氏不动杆菌10.68%；革兰氏阴性菌共64株，占比11.23%，其中金黄色葡萄球菌7.71%。阿米卡星、亚胺培南对各种病原菌均较敏感，美洛培南除对鲍氏不动杆菌不敏感外，对其他菌类均敏感；环丙沙星、庆大霉素对金黄色葡萄球菌均较为敏感，氨苄西林对肺炎克雷伯菌、大肠埃希菌、鲍氏不动杆菌、阴沟肠杆菌、铜绿假单胞菌的敏感性均较差。结论：小儿细菌性肺炎病原菌以革兰氏阴性菌为主，临床用药应以药敏试验为指导，合理使用抗生素，避免或减少细菌耐药性的产生。 【关键词】小儿细菌性肺炎；病原菌；耐药性 Analyzed the speciese of pathogens and drug resistance of children with bacterial pneumonia [Abstract]Objective: To investigate the pediatric bacterial pneumonia pathogens and drug resistance. Methods: January 1, 2010 -2012 on December 31 hospital 2382 cases of bacterial pneumonia in pediatric patients sputum culture samples to analyze the distribution of pathogens and drug resistance. Results: Children with bacterial pneumonia pathogens mainly Gram-negative bacteria, a total of 477, accounting for 83.45 percent, 26.44 percent among Klebsiella pneumoniae, Escherichia coli and 25.22%, Acinetobacter spp 10.68%; leather Gram-negative bacteria were 64, accounting for 11.23%, of which 7.71% of Staphylococcus aureus. Amikacin, imipenem compared to various pathogens sensitive to meropenem in addition to Acinetobacter spp insensitive, but on the other fungi are sensitive; ciprofloxacin, gentamicin against Staphylococcus aureus were more sensitive, Ampicillin against Klebsiella pneumoniae, Escherichia coli, Acinetobacter spp, Enterobacter cloacae, Pseudomonas aeruginosa are poor sensitivity. Conclusions: Children with bacterial pneumonia pathogens mainly Gram-negative bacteria, clinical treatment should be based on susceptibility testing as a guide, the rational use of antibiotics to prevent or reduce bacterial drug resistance. [Keywords] bacterial pneumonia in children; pathogens; drug resistance 小儿细菌性肺炎是儿科常见的感染性疾病，是婴儿时期的主要死亡原因之一，仅次于心脑血管疾病[1]。细菌性肺炎的治疗常