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磷脂酰丝氨酸的提取分离研究进展 research advance in extraction and separation of phosphatidylserine
56 CHINA0115ANDFATS 201lVol,36
No.3
油脂化工
磷脂酰丝氨酸的提取分离研究进展
李阅兵1,刘承初1,谢 晶1,李应森2,李家乐2.一,陈苏4
(1.上海海洋大学食品学院,上海201306;2.上海海洋大学省部共建水产种质资源发掘与
利用教育部重点实验室,上海201306;3.上海市高等学校水产养殖学E一研究院,
上海201306;4.美国焯安神经增长因子生物技术有限公司,美国)
摘要:磷脂酰丝氨酸作为人类大脑的益智物质,已经得到了广泛关注。主要对磷脂酰丝氨酸的提取
和纯化方法进行介绍。提取方法包括氯仿一甲醇法、叔丁基甲醚法、乙酸乙酯一乙醇法等。纯化的
方法涉及薄层色谱法、柱色谱法、高效液相色谱法等。磷脂酰丝氨酸提取工艺复杂。需使用大量有
机溶剂,今后需加强提取工艺的优化。
关键词:磷脂酰丝氨酸;溶血磷脂酰胆碱;提取;纯化;色谱;洗脱
文献标志码:A
中图分类号:TQ645;Q545
Researchadvanceinextractionand of
separation
LI Su4
Jiale2”,CHEN
Yuebin91,LIUChengchul,XIEJin91,LIYingsen2,LI
ofFoodScienceand Ocean 201
(1.College Technology,ShanghaiUniversity,Shanghai306,China;
of
of andUtilization Genetic Ocean
2.KeyLaboratory
Exploration Aquatic Resources,Shanghai
of 201 of
Division,E—Institute
University,MinistryEducation,Shanghai306,China;3.Aquaculture
201
ShanghaiUniversities,Shanghai306,China;4.ChainonNeurotrophinBiotechnologyInc.,American)
the substancesofhuman beenconcerned
nootmpics brain,has
Abstract:Phosphatidylserine,as widely.
Theextractionand methodsof wereintroduced.Theextractionmethodsin—
purification phosphatidylserine
eluded‘chloroform—methanol ethermethodand acetate—ethano
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