刺五加增强小鼠免疫功能的作用-西华师范大学学报自然科学版.PDFVIP

DOI :10.16246/j.issn.1673 -5072.1998.02.015 　19 2 　　　　 ( )　　　　1998 6 　Vol.19, No.2 　　 Journal of Sichuan Teachers College(Natural Science)　　　Jun.1998 FUNCTIONS OF ACANTHOPANAX SENTICOSIDES IN ENHANCING THE IMMUNITY OF MICE 黄秀兰 朱家媛 胡　宏 Huang Xiulan 　 　 Zhu Jiayuan Hu Hong (, 　637007) (Dept.of Pharmacology, North Sichuan Medical College, Nanchong　637007) 　　(S)、 ., S 、、. S . S . 　, , . 　R967 ABSTRACT 　The influence of acanthopanax senticosides(S)on theweight, cell numbers and stereological parameter of the immunity organs of the normal and immunity-inhibited mice are studied.The results reveal that S could increase the weight and cell numbers of the spleen and lymphoglandulae mesocoliae;and it could increae the whole volume of the spleen white pulp and lymphoglandulae cortex of mice.S could significantly resist the immuni- ty inhibition caused by cyclophophamide as well.Therefore the conclusion is reached that S could enhance the im- munity of mice. KEY WORDS　acanthopanax senticosides, cyclophophamide, immunity. [1] (acanthopanax senticosides;S) :、、. , 、、[ 2～4] ., [5] ., (cyclophopha- mide;CP), 、 , . 1　材料和方法 1.1　　 ml 5 mg, , 960604. , 961205. 　1997-10-09. 　　20　2 　　　　　　　　　　()　　　　　　　　　1998 1.2　 32 , 20～22g, , .4 : -1 -1 ();(100 mg ·kg );(100 mg ·kg ); -1 -1 (100 mg ·kg )+(100 mg·kg ). 1.3　　, 5 .24 h , , ., , (mg ·g-1 )., , .4 、 .5 μm , 200 μm (40 ); 50 μm (10 )1.5 , HE . , 、 (P0 ), () ()(P ).P P (/) s s 0 (/), (V0 =W/D ,