败血症休克的病理机制.pdfVIP

Pathologic Mechanisms of Pathologic Mechanisms of Septic Shock Septic Shock Kenneth J. Goodrum, Ph.D. OUCOM Topics Topics ● Definitions: SIRS,sepsis,shock,MODS ● Morbidity/mortality of Sepsis/Shock ● Pathogenesis of shock ● Microbial triggers(endotoxin, TSSTs) ● Cytokine and non-cytokine mediators of SIRS and shock ● Pathophysiology of shock ● Therapy Systemic Inflammatory Systemic Inflammatory Response Syndrome (SIRS) Response Syndrome (SIRS) ● Systemic inflammatory response