5-心血管-英-2015-5.ppt

Infective (bacterial) Endocarditis Endocarditis: bacteria directly invade the endothelium: heart valves, the rings of connective tissue that surround the valves, and the inner linings of the heart chambers. Local infection of bacteria ? less virulent ? mouth, GU or GI infection strong virulent (pyogenic)?wound infection Blood: bacteremia, septicemia, pyemia ? Cardiac abnormality or normal valves ? suppurative: vegetation，ulceration ?dysfunction of valves Subacute or acute infective endocarditis (SBE or ABE) Subacute infe