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牛磺酸影响胆固醇代谢的研究进展 Research progress of effect of taurine on cholesterol metabolism
5 7 Vol. 5 No. 7
2014 7 Journal of Food Safety and Quality Jul. , 2014
张 珊, 郭俊霞, 陈 文*
(, 100191)
摘 要: , ,
, ,
,
, /,
,
关键词: ; ; ; CYP7A1
Research progress of effect of taurine on cholesterol metabolism
*
ZHANG Shan, GUO Jun-Xia, CHEN Wen
(Department of Food Science , College of Arts and Science of Beijing Union University, Beijing 100191, China)
ABSTRACT: Taurine, a small molecule of sulfur-containing amino acid, was one of the common food
ingredients and rich in seafood. Taurine has an anti-atherosclerotic effect and is considered as a cardiovascular
cytoprotective agent since animal studies and clinical trials provide the evidence that taurine decreases
individuals serum total cholesterol level and atherosclerosis index. The present paper summarized the effect of
taurine on cholesterol metabolism from both of in vivo and in vitro experiments, and addressed the possible
mechanisms of cholesterol lowering effect of taurine via cholesterol clearance, cholesterol bioconversion to bile
acid, and bile acid excretion in feces, so as to provide a reference for the further study in taurine nutrition and
for the further utilization of taurine in functional foods.
KEY WORDS: taurine; c
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