PHARMACOLOGICAL MANAGEMENT OF COPD IN PATIENTS 慢性阻塞性肺疾病患者的药物治疗.pptVIP

CONCLUSIONS Beta–blockers and other cardiac drugs are safe in COPD Statins may improve COPD outcomes but proper trial data are needed Oral therapies produce more GI upset, oral corticosteroids long term are hazardous Inhaled corticosteroids do not seem to accelerate osteoporosis but some may induce pneumonia LAMA and LABA treatment is safe in COPD – anti-inflammatory therapy may improve cardiac outcomes On balance our treatments are more friend than foe * * SAFETY (BU) * Importantly, CCL3 and CXCL9 in lungs of patients afflicted from COPD were shown to correlate with COPD disease severity. (