feno测定在儿童咳嗽变异性哮喘与支气管肺炎鉴别诊断中应用.docVIP

精品论文 参考文献 FeNO测定在儿童咳嗽变异性哮喘与支气管肺炎鉴别诊断中应用 吴宏图 丁娴 高凤 曹兴丽 刘平 　　（江苏省淮安市第二人民医院儿科 江苏 淮安 223002） 　　【摘要】 目的：探讨咳嗽变异性哮喘患儿呼出气一氧化氮（FeNO）、CRP及血IgE水平变化及意义。方法：选择2013年1月至2014年12月就诊于淮安市二院儿科患儿，其中咳嗽变异性哮喘患儿30例（CVA组）， 支气管肺炎患儿30例（支肺炎组）以及25例健康对照儿（对照组），分别检测FeNO浓度、CRP及血IgE浓度水平，并进行分析比较。结果：CVA组患儿FeNO、CRP及IgE水平明显高于其他2组（Plt;0.05）；支肺炎组患儿CRP及血IgE水平高于对照组（Plt;0.05）,而FeNO与对照组相比无明显差异。结论：在CVA诊断中，FeNO比CRP及血IgE特异性更高，同时FeNO为儿童咳嗽变异性哮喘和支气管肺炎鉴别诊断提供了一定参考依据，感染与免疫因素在儿童CVA中起了一定作用。 　　【关键词】 儿童；咳嗽变异性哮喘；呼出气一氧化氮 　　【中图分类号】R44 【文献标识码】A 【文章编号】2095-1752（2015）09-0076-03 　　The identified diagnosis Appliance of FeNO detection between children cough variant asthma and brochipneumonia Wu Hongtu, Ding Xian,Gao feng,Cao Xingli,Liu ping Huaian Second Peoplersquo;s Hospital Huaian City Jiangsu Province,223002 ,China 　　【Abstract】Objective To explore the change of FeNO,CRP and IgE and their significance in children cough variant asthma. Methods eighty-five ?children patiants from July 2012 to June 2013 were enrolled. They were divided into three groups respectively, 30 CVA group, 30 brochipneumonia infants group and 25 heath controls group. The level changes of FeNO ,CRP and IgE were detected and analysed comparedly. Results level of FeNO,CRP and IgE were obviously higher in CVA group than those in brochipneumonia and health group controls (Plt;0.05); Level of CRP and IgE in bronchipneumonia group were higher than those in health controls,but level of FeNO have no differences between bronchipneumonia group and health controls. Conclusion FeNO measurement is of great value in the diagnosis of CVA, in which the specificity of FeNO test was higher than CRP and IgE. At the same time,FeNO detection,CRP and IgE are helpful to a certain extent to identify CVA and brochipneumonia in providing diagnosis proof. Immune injury and infections play a certain role in Children Cough Variant Asthm