不规则抗体筛查在输血患者中应用价值研究.docVIP

精品论文 参考文献 不规则抗体筛查在输血患者中应用价值研究 (商丘市第一人民医院输血科 河南商丘 476100) [摘要] 目的:研究不规则抗体筛查在输血患者内的应用价值。方法:将我院2014年8月至2015年12月行门诊与住院的140例预行输血患者随机分为对照组70例，使用凝聚胺方法进行不规则抗体筛查；实验组70例，使用微柱凝胶方法进行不规则抗体筛查。比较两组患者不规则抗体筛查结果的符合度、阳性检出率。结果:对照组经筛查显示假阳性率为57.9%高于实验组的0.0%，对照组与抗人球蛋白法的筛查结果符合度差于实验组，差异显著（P＜0.05）；血液系统疾病的不规则抗体筛查结果内阳性检出率高于其他类型疾病，差异显著（P＜0.05）。结论:输血前给予患者不规则抗体筛查能有效减少溶血性输血反应发生风险，保证输血有效性与安全性。 [关键词] 不规则抗体筛查；输血；应用价值 Irregular antibody screening application value in patients with blood transfusion Lisa (shangqiu first peoples hospital of blood transfusion Henan shangqiu, 476100) [abstract] objective: to study the irregular antibody screening application value in patients with blood transfusion. Methods: from August 2014 to December 2015 rows of outpatient and hospitalization were randomly divided into control group, 70 cases of 140 patients with preventive blood transfusion, condensed amine method is used for irregular antibody screening; Experimental group 70 cases, using micro column gel method for irregular antibody screening. Compare two groups of patients with irregular antibody screening results conform to the degree, positive detection rate. Results: the control group by screening showed false positive rate is 57.9% 0.0% higher than that of the experimental group, control group and anti globulin method of screening results conform to the degree of difference in the experimental group, significant difference (P lt; 0.05); Blood system diseases of irregular antibody screening results in positive detection rate is higher than other types of diseases, the significant difference (P lt; 0.05). Conclusion: patients with irregular antibody screening before blood transfusion can effectively reduce the risk of hemolytic transfusion reaction, ensure transfusion efficacy and safety. [key words] irregular antibody screening; Blood transfusion. Application value 近年来，不规则抗体引发的迟发性溶血性输血反应发生风险越来越高，但随着现代输血技术的快速发展，血型检测技术、配血技术、输血前检验技术逐渐向标准化、规范化发展，输血患者在输血过程中溶血反应发生率有所降低[1]。不规则抗体是指包含红细胞血型的同种抗体、自身抗体，多种因素均可引发不