MRI及MRS诊断单发急性炎性脑脱髓鞘疾病的应用价值探析.docVIP

精品论文 参考文献 MRI及MRS诊断单发急性炎性脑脱髓鞘疾病的应用价值探析 杜碧茵 　　(广州市精神病医院 510370) 　　【摘要】目的 研究探讨单发急性炎性脑脱髓鞘疾病的影像学特征及MRI、MRS在疾病诊断中的应用价值。方法 选取我院近年来收治的单发急性炎性脑脱髓鞘疾病患者9例作为研究对象，回顾性分析患者的基本临床资料和影像学检查结果，并对其中枢神经系统的影像学征象进行分析，讨论其临床特征性。结果 9例患者通过MRI诊断可见，1例患者病灶位于基底节区域，8例患者位于额顶叶皮层下白质，病灶边缘光滑，形状规则类圆形，结构层次典型，由病灶中心、环壁与水肿区构成，DWI和FLIAR、ADC图均为病变中心低信号，周边高信号；T1WI中心低信号，T2WI中心高信号。经增强扫描，病灶呈现出不规则的开环强化，且无显著占位效应。经MRS诊断，所有患者病变中心区域均有Cho峰增加(Cho／Cr增加)与NAA峰降低(NAA／Cr值降低)的表现。除此之外，3例患者有mI峰增加情况，5例患者有Cr峰降低情况。所有患者经相关治疗复查可见病灶体积、区域缩小，Cho峰降低和NAA峰恢复。结论 单发急性炎性脑脱髓鞘疾病的患者经核磁共振检测，能清晰地观察到病灶的位置、数目、形态、信号特点等MRI表现，还可以在MRS诊断中准确显示NAA峰、Cho峰、Cr峰、mI峰的变化情况，帮助医生从患者的影像学征象的特征变化中准确诊断并判断疾病的进展。 　　【关键词】单发急性炎性脑脱髓鞘疾病 MRI MRS 临床应用 　　【中图分类号】R742 【文献标识码】A 【文章编号】2095-1752（2014）15-0251-02 　　MRI and MRS diagnosis of single acute inflammatory demyelinating disease of the brain Value Analysis 　　【Abstract】Objective Study investigated the characteristics and MRI imaging single acute inflammatory demyelinating disease of the brain, MRS applications in disease diagnosis. Methods Admitted to our hospital in recent years, single acute inflammatory demyelinating disease of the brain in patients with nine cases for the study, the basic clinical data and imaging findings were retrospectively analyzed patients and analyzed for signs of central nervous system imaging discuss its clinical characteristic. Results By MRI diagnosis of basal ganglia lesions in one case, the white matter is located eight cases, the lesion edges smooth, round shape rules, hierarchy typical. DWI and FLIAR, ADC figure are low signal lesion center, the surrounding high signal; T1WI center of low signal, T2WI high signal center. Through enhanced scan showed irregular lesions strengthening the open-loop and no significant mass effect. After MRS diagnosis, all patients had lesions in the central region increased Cho and NAA peak lower peak performance. Three patients had a peak increase in mI, 5 patients had lower Cr peak condition. Review o