麻省理工学院 生物材料课程 Lecture 9 Surface Modification of Biomaterials.pdfVIP

3.051J/20.340J 1 Lecture 9: Surface Modification of Biomaterials Purpose: alter surface properties to enhance performance in biological environment while retaining bulk properties of device Specific Objectives: 1. clean a surface 2. reduce/eliminate protein adsorption • reduce undesirable/uncontrolled responses to implants extracorpeal devices C3b/IgG adsorption ⇒activation of WBCs • reduce nonspecific adsorption on biosensors bioassays (noise