5891例输血前患者抗体检测结果分析.docVIP

精品论文 参考文献 5891例输血前患者抗体检测结果分析 屈雅川1 周建月2 (1广西医科大第三附属医院 广西南宁 530031;2广西医科大第一附属医院 广西南宁 530021） 【中图分类号】R457.1 【文献标识码】A 【文章编号】1672-5085（2010）28-0253-03 【摘要】 目的 通过对输血前患者进行不规则抗体检查并对阳性结果进一步确定分析，以保证临床安全输血。方法对本院输血前患者进行不规则抗体筛查，阳性者用盐水、酶、抗人球法进行抗体特异性鉴定。结果5891例标本阳性共20例，阳性率为0.34%，分别为抗-D抗体4例，抗-E抗体5例，抗-C、e抗体3例，抗-C、抗-A1抗体各2例，抗-c、E抗体、抗-C、E抗体 、抗-H、抗-M抗体各1例；椐分析，不同人群阳性率存在差异。结论输血前不规则抗体检查可避免溶血性输血反应的发生，确保输血安全。 【关键词】 不规则抗体 筛查 输血 5891 cases of blood transfusion before the antibody test results of patients Qu Ya-chuan ，The Thirst Affiliated Hospital of Guangxi Medical University, Nanning 530031，China Zhou Jian-yue The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China 【Abstract】 Objective Irregular antibodies in patients before transfusion and the positive results of inspections of further defined to ensure the safety of clinical blood transfusion. Methods Pre-hospital blood transfusion in patients with irregular antibody screening, positive use of salt, enzymes, anti-human antibody specific identification of the ball method. Results 5891 cases of samples were positive in 20 cases, the positive rate was 0.34%, respectively, of anti-D antibodies in 4 cases, 5 cases of anti-E antibody, anti-C, e antibody in 3 cases, anti-C, anti-A1 antibody in 2 cases, anti-c, E antibody, anti-C, E antibodies, anti-H, anti-M antibodies in 1 case; noted in the analysis of differences in positive rates of different groups of people. Conclusion Irregular antibody test before transfusion to avoid hemolytic transfusion reaction, to ensure the safety of blood transfusion. 【Key words】 Irregular antibodies Screening Blood transfusion 不规则抗体是指红细胞ABO血型系统以外的抗体，多为IgG抗体，是引起免疫性溶血性输血反应、新生儿溶血病（HDN）、血型鉴定困难等主要原因。输入ABO、Rh血型不合的血液或妊娠以及自身免疫性疾病等因素，均可导致患者血液中产生红细胞血型不完全IgG抗体［1］。而且，任何Rh系统IgG抗体都可能引起HDN。所以，输血前不规则抗体筛查，特别对那些较高发生率人群如孕产妇、有输血史患者等的安全用血，尤为必要。自2007年9月以来本院对所有需要输血的患者进行输血前不规则抗体筛查，总共5891例，阳性结果20例，现报告如下。 1. 材料与方法 1.1标本 来自本院 2007年6月至2009年12月住院申请输血患者共5891例，其中男3043（5