宫腔镜手术治疗子宫瘢痕处妊娠的Meta分析.docVIP

精品论文 参考文献 宫腔镜手术治疗子宫瘢痕处妊娠的Meta分析 丁悦 程丽琴 王敏 　　（深圳市第七人民医院妇产科 广东 深圳 518081） 　　【摘要】 目的：评价宫腔镜手术与传统清宫术治疗子宫瘢痕处妊娠的有效性和安全性。方法：按照循证医学的要求全面计算机检索Cochrane图书馆、Medline、PubMed、EMBASE、万方医学数据库、维普数据库、知网CNKI和中国生物医学数据库CBM，检索时限为1978年1月1日至2015年2月28日，同时进行文献追溯，根据摘要查找相关文献并获取全文，收集宫腔镜手术与传统清宫术治疗子宫瘢痕处妊娠的随机对照试验。结果：检索到符合纳入标准的随机对照试验文献6篇，病例总数424例，Meta分析结果显示：宫腔镜手术治疗的术中出血量[95%CI:-3.50(-4.57，-2.42)，Plt;0.00001]和血清beta;-HCG降至正常所需时间[95%CI:-2.31(-3.69，-0.93)，P=0.001]和住院时间[95%CI:-1.99(-3.12，-0.86)，P=0.0005]均??著少于传统清宫术治疗组。结论：宫腔镜手术较传统清宫术治疗子宫瘢痕处妊娠中有效性与安全性更高，术中出血量少，血清beta;-HCG降至正常所需时间及住院时间短，可作为临床优先选择的治疗方法。 　　【关键词】 宫腔镜手术；子宫瘢痕妊娠；随机对照试验；Meta分析 　　【中图分类号】R713 【文献标识码】A 【文章编号】2095-1752（2015）21-0209-04 　　Meta-analysis Of Hysteroscopic Surgery For Cesarean Scar Pregnancy Ding Yue,Cheng Liqin,Wang Ming. 　　Department of Obstetrics and Gynecology of the Seventh Peoplersquo;s Hospital of Shenzhen ,Shenzhen 518081,China 　　【Abstract】Objective The objective of this study was to evaluate the efficacy and safety of the therapy of cesarean scar pregnancy (CSP) by hysteroscopic surgery with contrast to that by curettage. Methods According to the requirements of Evidence-based medicine, thoroughly searched in Cochrane Library, Medline, PubMed, EMBASE, WANFANG medicine database, CNKI and China Biology Medicine database(CBM) in the period of Jan 1st of 1978 to Feb 28 of 2015, also searched in relevant documents by reviewing the above abstracts, for randomized controlled trials(RCTs) of hysteroscopy surgery and traditional curettage treatment of CSP. Results 6 studies involving 424 patients were included. Meta-analysis showed that the bleeding volumes[95%CI:-3.50(-4.57，-2.42)，Plt;0.00001], recovery time of serum beta;-HCG content to normality[95%CI:-2.31(-3.69，-0.93)，P=0.001] and hospitalization time[95%CI:-1.99(-3.12，-0.86)，P=0.0005] were significantly less in hysteroscopy surgery group compared with curettage treatment group. Conclusion Compared with curettage for CSP, hysteroscopic