自拟祛疣颗粒治疗多发性跖疣的疗效及对免疫功能的影响-环球中医药.PDFVIP

摇摇406 环球中医药2016年4 月第9卷第4期摇 Global Traditional Chinese Medicine,April2016,Vol郾9,No郾4 ·论著 · 自拟祛疣颗粒治疗多发性跖疣的疗效及对 免疫功能的影响 孔宇虹摇 李元文摇 任琳摇 孙占学摇 赵雅静 揖摘要铱摇 目的摇 观察自拟祛疣颗粒治疗多发性跖疣的临床疗效及其对机体免疫功能的影响。 方法摇 采用随机数字表分组法将60例多发性跖疣患者分为治疗组和对照组各30例,治疗组采用中 药祛疣颗粒每天2剂(共4袋),其中1剂开水冲服,每次1袋,每天2次;另1剂加枯矾10 g,加入热 水冲化后浸泡患足,每次40分钟,每天1次,2周为一个疗程,2个疗程后观察并判定疗效。 对照组 采用液氮冷冻治疗,每2周1次,治疗4周后观察并判定疗效。 结果摇 治疗组总有效率为89.7%,明 显高于对照组(55.2%),经检验,两组总有效率比较具有统计学意义(P0.05);对T细胞亚群的影 + + + + 响比较,治疗组对外周血细胞免疫有一定的改善作用,CD4 增高,CD8 降低,CD4 / CD8 增高,而对 照组对外周血T细胞亚群分布几乎无影响;两组复发率的比较,治疗组复发率7.7%,明显优于对照 组(50%)。 结论摇 祛疣颗粒内服加外用治疗多发性跖疣具有安全有效,复发率低的特点,疗效明显 优于冷冻治疗。 揖关键词铱摇 跖疣;摇 寻常疣;摇 中药;摇 免疫功能;摇 冷冻 揖中图分类号铱摇 R249摇 揖文献标识码铱摇 A摇 doi:10郾3969/ j郾issn郾1674鄄1749郾2016郾04郾006 Effect of the self鄄made Quyou granules in the treatment of multiple verruca plantaris and its influence on immune function摇 KONG Yu鄄hong,LI Yuan鄄wen,REN Lin,et al.摇 Beijing University of Chinese Medicine,Beijing 100029,China Corresponding author:LI Yuan鄄wen,E鄄mail:yuan鄄wen@ 揖Abstract铱摇 Objective摇 Toobservetheeffectof Quyougranulesinthetreatmentof multipleverruca plantaris and its effects on the immune function. Methods摇 60 patients with multiple verruca plantaris were divided into treatment group and control group accordingtorandom numberstable,30 casesin each. Treatment group was treatedwith traditional Chinese medicine (TCM) Quyou granules2 doses (4 bags), of which 1bagaddingtoboilingwater,1bageachtime,2timesaday;theother 1plusalum10 g,adding hot water and soaking the affected foot,40 minutes each time, 1 times a day,2 weeks for a course of treatment,the curative effect was observed after2 coursesof treatment. The control groupwastreatedwith liquid nitrogen,1times per2 week,4 weeks after treatment,the curative effect was observed. Results摇