降钙素原对新生儿感染的诊断价值.pdfVIP

·综述· 降钙素原对新生儿感染的诊断价值 齐华雪(综述) 陈平洋(审校) 【摘要】新生儿感染是引起新生儿死亡的重要原因。目前感染检测指标对新生儿感染的诊断在灵敏 性、特异性等方面各有差异。近年来，降钙素原(procalcitonin，PCT)被广泛用于各种感染性疾病的诊断，对 新生儿感染的早期诊断的灵敏性、特异性均较高，与新生儿感染的严重程度、感染的发展及疾病的预后具 有相关性，可用来衡量治疗效果及预后评估。血清PCT在新生儿期不受母体血清PCT水平高低和窒息缺 氧损伤引起的急性炎症反应的影响，仅与新生儿自身细菌感染严重程度有关，对新生儿感染的诊断具有特 殊意义。 【关键词】 降钙素原；新生儿；感染 of in of infection 11Ievalue neonatal procalcitonindiagnosis Q／Hua-xue．C删Ping-yang．Departmentof Second CentralSouth Neonatology．theXiangya of University，Changsha4loon，China Hospital Neonatalinfectionisoneofthe reasonsfornewborns current 【Abstract】 important mortality．m indicatorsofneonatalinfectionhavedifferencesinthe and recent diagnosis sensitivityspecificity，respectively．In showedthatthe usedinthe ofvariousinfectiousdiseases．Studies years．procalcitonin(PCT)iswidely diagnosis Pcrhad and inthe ofneonatalinfection．SerumPCTlevelis highersensitivityspecificityearlydiagnosis associatedwiththe ofneonatal andthe ofthedisease．Itcanbeused infection．the severity developmentprognosis to andthe the of serumpCTisnotaffected evaluatetheeffectoftreatment neonatal．the prognosis．Duringperied which and itis thelevelofmaternalandtheacute caused bv inflammatoryresponse byinjuriesasphyxia，and associatedwiththe ofnewbornbacterialinfection．PCThas tothe of severity specialsignificancediagnosis neonatalinfection． words】Procalcitonin：Newborn：Infection 【Key 新生儿感染早期症状不典型