近年病原微生物实验室获得性感染病例分析及其控制策略的初步研究.pdfVIP

近年病原微生物实验室获得性感染病例分析 及其控制策略的初步研究 魏强 李晓燕 王雷 卢选成盖孟楠武桂珍侯培森 [摘要] 目的 分析研究2000-2009年文献报道的引起全球病原微生物实验室获得性感染病 例的病原微生物种类、感染途径、发生原因并初步探讨病原微生物实验室获得性感染预防控制策略。 方法 选择PubMed、Embase、Biosis以及涵盖SCIE、SSCI、CPCI-S和CPCI-SSH的Web of Science作为 数据源，以Laboratory-acquired(associated)infections为检索词，检索2000-2009年发表的有关实验室 获得性感染文献后，对获取信息和数据进行整理、分析、研究。结果 近10年来引起实验室获得性感 染病例的病原微生物有l9种，其中细菌15种，占78.9％;病毒4种，占21.1％。报道病例83例，其中 细菌性病例60例，占72. 3％;病毒性病例23例，占27.7％。感染途径以摄入和吸人性感染为主，分 别占32. 5％和31.3％，感染主要原因为意外事故，占47.0％。结论 近年来，病原微生物实验室获得 性感染病例仍时有发生，感染的主要原因为意外事故，暴露出实验室工作人员安全意识和规范操作方 面的缺陷。实验室工作人员注重安全意识，遵守安全操作规程，仍是预防控制实验室获得性感染发生 的关键。 实验室感染;感染控制 Preliminary studies on pathogenic microorganisms laboratory-acquired infections cases in recent years and its control strategies WEI Qiang LI Xiao-yan WANG LeiLU Xuan-cheng JIANG Meng- nan WU Gui-zhen HOU Psi-senChinese Center for Disease Control and Prevention 102206, China [Abstract] Objective To analyze and study types, infections routes and causes of global pathogenic microorganisms laboratory-acquired infections cases reported in the literatures from 2000 to 2009 and to discuss prevention and control strategies. Methods ①Pathological observation of hepatic specimens: hepatic tissue pathogenic microorganisms laboratory-acquired infections. Methods PubMed, Embase, Biosis and Webs of Science covering SCIE, SSCI, CPCI-S and CPCI-SSH are chosen as data sources, “laboratory- acquired (associated) infections” are searched as the key words to search laboratory-acquired infections literature published from 2000 to 2009, from which information and data are accessed to be collected, analyzed and researched. Results There are 19 species of pathogenic microorganisms causing laboratory- acquired infections in the last 10 years, including 15 species of bacteria, accounting for 78.9％ ; 4 species of virus, accounting for 21.1％. There are 83 cases reported, of which there are 60 bacterial cases, accounting for 72. 3％ ; and 23 virus cases,