连花清瘟胶囊治疗甲型H1N1流感的临床研究.docVIP

连花清瘟胶囊治疗甲型H1N1流感的临床研究 ? 专家论坛?2010年10月第7卷第30期 连花清瘟胶囊治疗甲型H1N1流感的临床研究 欧阳茴香,唐清艳,陈永忠,魏瑜,李国术 (湖南省衡阳市中心医院急诊科,湖南衡阳421001) 【摘要】目的:观察连花清瘟胶囊治疗甲型H1N1流感的疗效及安全性.方法:随机对照分析2009年9月～2010年3月 应用连花清瘟胶囊,奥司他韦胶囊,氨咖黄敏胶囊治疗甲型HIN1流感患者174例,对比观察连花清瘟胶囊的体温 疗效,证候疗效,退热起效时间以及不良反应.结果:体温疗效显效率连花清瘟组和奥司他韦组分别为72.4%, 75.7%,两组之间无显着性差异(Pgt;0.05),均明显高于氨咖黄敏组(48.3%)(火O.05);临床证候的显效率连花清瘟组 和奥司他韦组分别为75.9%,79.3%,两组之间无显着性差异(Pgt;0.05),均明显高于氨咖黄敏组(55.2%)(Plt;0.05):连 花清瘟组退热起效时间优于奥司他韦组(P=-0.032);三组不良反应发生率均较低.结论:连花清瘟胶囊治疗甲型H1N1 流感与奥司他韦一样效果显着,安全性好. 【关键词】甲型H1N1流感;连花清瘟胶囊;奥司他韦;氨咖黄敏 f中图分类号】R511.7【文献标识码】A【文章编号】1673—721O(2010)10(c)一006—03 ClinicalobservationofLianhuaQingwenDepartmentofEmergency,Cap- sulesintreatmentoftheinfluenza栅1N1 0UYANGHuixiang,TANGQingyan,CHENYongzhong,剧yH,LIGuoshu (DepartmentofEmergency,CentralHospitalofHengyangCity,Hengyang421001,China) [Abstract]Objective:ToobservetheclinicaleffectandsafetyofLianhuaQingwenCapsulesintreatmentoftheinfluenza MH1N1.Methods:Thedataof174admittedpatientswiththeinfluenzaA/H1N1whoweretreatedwithLianhuaQingwen Capsules,OsehamivirCapsules,Paracetamol,Caffein,AtificialCow—bezoarandChlorphenamineMaleateCapsulesfrom September2009toMarch2010wasrandomlycollected.Theeffectiverateoftemperatureeffecttest,TCMsymptomstest andsideeffectsofLianhuaQingwenCapsuleswerecompared.Results:Theeffectiverateoftemperatureeffecttestin LianhuaQingwenCapsulesgroupandOseltamivirCapsulesgroupwere72.4%and75.7%.showingnosignificantdiffer- ence(Pgt;0.05),whichwassignificantlyhigherthanthat(48-3%)inParacetamol,Caffein,AtificialCow-bezoarandChlor- phenamineMaleateCapsulesgroup(Plt;0.05);theeffectiverateofTCMsymptomstestinLianhuaQingwenCapsulesgroup andOsehamivirCapsulesgroupwere75.9%and79_3%,showingnosignificantdifference(gt;0.05),whichwassignificantly higherthanthat(55.2inParacetamol,Caffein,AtificialCow—bezoarandChlorphenamineMaleateCapsulesgroup(Plt;0.05). TheaveragetemperatureeffecttimesofLianhuaQingwenCapsulesgroupandOsehamivirCapsulesgroupwerehighlysig— nificantdifferencesinstatistics(P=O.032)betweengroups.Side