基层医院临床药师干预抗菌药合理使用效果分析.pdfVIP

　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 药物与临床　 基层医院临床药师干预抗菌药合理使用效果分析 陈娟英　 周利平　 (湖州市练市医院药剂科　 浙江湖州313013) 摘　 要　 目的:探讨基层医院临床药师干预抗菌药合理使用的效果。 方法:对我院临床药师干预前(2012年9 月~2013年2 月)和干预后(2013年3~8 月)各139例住院患者的抗菌药合理使用情况进行分析评价,总结临床药师参与临床的方式和效 果。 结果:临床药师干预后抗菌药使用率为33.1%,低于干预前的78.4%(P 0.05);干预后各科室用药率均低于干预前,尤 以呼吸科降低最多,差异均有统计学意义(P0.05);各科室用药强度均≤40;临床药师干预后用法用量不合理率(6.5%)和 用药疗程不合理率(6.5%),均低于干预前(P0.05);标本送检率(47.8%)高于干预前的24.8%(P 0.05)。 结论:基层医 院临床药师对抗菌药使用进行干预,有助于临床合理用药。 关键词　 抗菌药;临床药师;干预;基层医院;合理用药 中图分类号:R97　 　 文献标识码:A　 　 文章编号:1008-049X(2014)03-0460-03 Effect of Clinical Pharmacist Intervention on Antibiotics Rational Use in Primary Hospitals ChenJuanying,Zhou Liping (Department of Pharmacy,Lianshi Hospital of Huzhou,Zhejiang Huzhou313013,China) ABSTRACT　 Objective:To explore the effect of clinical pharmacist intervention on the antibiotics rational use in primary hospital. Methods:Before the intervention (September2012 to Feburary2013) and after the intervention (March to August2013) by clinical pharmacists,totally278 patientstreatedbyantibacterialdrugswereanalyzedtosummarizetheparticipationwaysandinterventioneffect of clinical pharmacists.Results:The antimicrobial usage rate after and before the intervention was 33.1% and78.4%,respectively with statistically significantdifference (P0.05),andineveryinvestigateddepartment,theusagerateaftertheinterventionwaslower than that before the intervention (P0.05),especially in the respiration department,the reduction was the most obvious. The drug use strength in all departmentswas lower than40. The irrational dosage and administrationratewas6.5%,andtheunreasonablerate of the medication coursewas6.5% after the clinical pharmacist intervention,whichwasmuchlower thanthosebeforethe intervention (25.7% and22.9%,respectively). The specimen submissionratewas47.8% aftertheintervention,whichwashigherthanthat be- fore the intervention (24.8%) with statistically significant difference (P 0.05). Conclusion:Clinical