急性心肌梗死患者住院治疗的药物分析.docVIP

精品论文 参考文献 急性心肌梗死患者住院治疗的药物分析 冯碧容 　　（四川省南充卫生学校附属医院内科 四川南充 637000） 　　【摘要】目的：探讨急性心肌梗死患者住院药物治疗。方法：本次选取急性心肌梗死患者100例，均为我院心血管内科2014年3月至2015年4月收治，随机分组，就阿司匹林单用治疗（对照组，n=50）与联用氯吡格雷治疗（观察组，n=50）效果展开对比，回顾临床资料。结果：观察组选取的急性心肌梗死病例梗死后心绞痛率为2%，无再发心肌梗死及死亡事件，对照组分别为10%，6%，8%，有统计学差异（Plt;0.05）。观察组血管再通率为46%，对照组为44%，无明显差异（Pgt;0.05）。观察组再闭塞率为4%，对照组为16%，有统计学差异（Plt;0.05）。两组治疗前LVEF无明显差异，治疗后观察组明显升高，对照组不明显，组间有统计学差异（Plt;0.05）。两组凝血指标疗前无差异，疗后APTT均升高（Plt;0.05），但组间无差异（Pgt;0.05），两组PT、Plt治疗后与疗前均无差异（Pgt;0.05）。结论：氯吡格雷与阿司匹林联合治疗急性心肌梗死，未增加出血风险，可使住院期间患者心血管事件率降低，最大程度保障预后，对提高临床效果意义显著。 　　【关键词】急性心肌梗死；阿司匹林；氯吡格雷 　　【中图分类号】R45 【文献标识码】A 【文章编号】1007-8231（2015）08-0019-02 　　【Abstract】Objective To study the drug treatment in patients with acute myocardial infarction (mi) was in the hospital. Methods The selected 100 cases of patients with acute myocardial infarction (mi), all are our cardiovascular internal medicine in March 2014 to April 2015, a randomized, as aspirin therapy alone (the control group, n = 50) and combination with clopidogrel therapy (observation group, n = 50) contrast effect, review of clinical data. Results Observation group selected cases of acute myocardial infarction angina pectoris after infarction rate was 2%, no recurrence of myocardial infarction and death, the control group were 10%, 6%, 8%, statistically significant (Plt; 0.05). Blood vessels to the 46% rate of observation group and control group was 44%, no significant difference (P gt; 0.05). Observation group and occlusion rate was 4%, control group was 16%, statistically significant (P lt; 0.05). No obvious difference was found between the two groups before treatment LVEF, increased significantly after treatment group, control group is not obvious, the difference between groups (P lt; 0.05). Coagulation index before treatment differences between the two groups, APTT were increased after treatment (P lt; 0.05), but no difference between groups (P gt; 0.05), two groups of PT, Plt and healing after trea