戊型病毒性肝炎137例临床分析.docVIP

精品论文 参考文献 戊型病毒性肝炎137例临床分析 朱永兵 刘新矿 孙方明 　　（安徽省淮南市第一人民医院感染病科 232007） 　　【摘要】目的 探讨137戊型肝炎的临床特征。方法 回顾性分析137例戊型病毒性肝炎患者的流行病学资料和临床特征。结果 137例急性戊型肝炎患者中男女之比4.27：1；40～65岁以上者102例(74.5%)；职业分布主要为农民108人(78.8%)；3～5月份发病患者数为73例(53.3%)；随患病年龄增加,ALB水平呈下降趋势,各组比较均有显著差异；重叠乙型肝硬化和酒精肝组的黄疸和病程明显高于单纯戊肝组。结论 戊型肝炎病毒性以散发为主，主要见于成年人、男性，农村人口高发,有春季发病高峰。大多数患者预后良好,乙肝肝硬化和酒精肝基础上叠加戊肝病毒感染可能是影响患者预后的重要因素。 　　【关键词】 戊型肝炎 流行病学特征 临床特点 　　【中图分类号】R512.6 【文献标识码】A 【文章编号】2095-1752（2014）20-0133-02 　　 Clinical analysis of 137 patients with hepatitis E 　　ZHU yong-bing, LIU xin-kuang ,SUN fang-ming 　　Department of Infectious Diseases, First Peoplersquo;s Hospital, Huainan, 232007, Anhui, China 　　Corresponding author: ZHU yong-bing, Email:amuzyb2005@ 　　【Abstract】Objective To observe the clinical characteristics of patients with hepatitis E. Methods The clinical data 0f 137 patients with hepatitis E was collected and analyzed retrospectively. Results the gender ratio of male to female was 4.27:1;the patients aged from 40 to 65-year old were the most(74.5%); the spring was the main morbidity season; the farmers was the main occupation of patients. The decreased level of ALB was associated with older age. The prevalence of jaundice and disease course in the group of hepatitis E infection accompanied by hepatitis B cirrhosis and alcohol hepatitis were higher than others. Conclusion Five epidemiological characteristics, including sporadic, adult, male, farmers and spring, are found to be associated with hepatitis E infection. The prognosis of disease in the majority of patients is favorable, and coexistence with hepatitis B cirrhosis and alcohol hepatitis can be seen as the factors which affect the prognosis. 　　【Key words】Hepatitis E Epidemiological features Clinical features 　　戊型肝炎为经粪-口途径传播的病毒性肝炎。近年来随着甲、乙型肝炎逐渐得到控制，戊肝发病呈上升趋势。本文通过总结我院收治的137例戊型肝炎病例的临床资料, 就其流行病学及临床特点做分析、报道如下。 　　1.资料与方法 　　1.1研究对象 选取2006年1月至2013年12月在我院诊断为急性戊型肝炎的住院患者137例, 诊断符合2000年西安全国传染病与寄生虫病学和肝病学术