强脉冲光联合点阵铒激光对痤疮后增生性瘢痕的有效性与安全性分析.docVIP

强脉冲光联合点阵铒激光对痤疮后增生性瘢痕的有效性与安全性分析 赵思成 赵翠杨 夏丹英 张春梅 上海交通大学附属医学院苏州九龙医院 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 研究分析强脉冲光联合点阵铒激光对痤疮后增生性瘢痕的有效性与安全性。方法 选择上海交通大学附属医学院苏州九龙医院2013年8月-2016年7月收治的135例痤疮后增生性瘢痕患者。采用随机数字表法将其分为强脉冲组、点阵组、联合治疗组, 每组45例, 比较治疗前和2次治疗后的疗效、温哥华瘢痕评价量表 (VSS) 评分以及不良反应情况和误工期。结果 3组治疗有效率比较, 差异无统计学意义 (P>0.05) , 但治疗后3组患者色泽、血管分布、厚度、柔软度和VSS评分比较, 差异有统计学意义 (P<0.05) , 并均有下降趋势。联合治疗组2次治疗后色泽、血管分布、厚度、柔软度和VSS评分与强脉冲组和点阵饵激光组比较, 差异有统计学意义 (P<0.05) , 联合治疗组各项指标低于其他两组。治疗后3组患者的生活质量评分比较, 差异有统计学意义 (P<0.05) 。治疗后联合治疗组的自我感知、情感功能、痤疮症状、社会功能等生活质量评分与同时期的强脉冲组和点阵铒激光组比较, 差异有统计学意义 (P<0.05) , 联合治疗组各指标均高于其他两组。联合治疗组的误工期与强脉冲组和点阵铒激光组比较, 差异有统计学意义 (P<0.05) , 联合治疗组均低于其余两组, 但3组不良反应发生率差异无统计学意义 (P>0.05) 。结论 强脉冲光联合点阵铒激光治疗痤疮瘢痕具有非常好的疗效, 治疗副作用较少, 安全性高, 同时能够降低误工期, 具有广阔的临床应用前景。 关键词： 强脉冲光; 点阵铒激光; 痤疮; 瘢痕; 收稿日期：2016-11-21 Efficacy and safety of intense pulsed light and erbium fractional laser in treating acne scar Si-cheng Zhao Cui-yang Zhao Dan-ying Xia Chun-mei Zhang Suzhou Jiulong Hospital Affiliated to Shanghai Jiao Tong University; Abstract： Objective To study the efficacy and safety of intense pulsed light and erbium fractional laser in treating acne scar. Methods In this study, 135 cases of acne scar patients from August 2013 to July 2016 were randomly divided into strong pulse group (n = 45) , lattice group (n = 45) and combined treatment group (n = 45) .Treatment efficacy, VSS score, adverse reaction and duration for delayed work were compared before treatment and after twice of treatment. Results There were no significant differences in the efficiency of treatment among the three groups (P > 0.05) . There were significant differences in the color, vascularity, thickness, softness and VSS score among the three groups after treatment (P < 0.05) , and there was a significant decrease in the color and vascularity.Color, vascular distribution, thickness, softness and VSS scores after twice of treatment in the combined treatment group were significant different fr