某院清洁切口围术期抗菌药物预防性应用分析.docVIP

精品论文 参考文献 某院清洁切口围术期抗菌药物预防性应用分析 李艳萍 陆婷婷 马春华 赵跃 文佳 张秀玲 邹艳 　　（四川省绵阳市中心医院医院感染管理科 四川 绵阳 621000） 　　【摘 要】目的：调查了解2010-2014年我院围手术期清洁切口（I类切口）抗菌药物预防性应用的现状，为临床合理使用抗菌药物提供建议。方法：回顾性分析2010年1月-2014年12月我院抽查的1184份含清洁切口（I类切口）患者的临床病历资料，分析围手术期抗菌药物的使用情况。结果：共调查1184例清洁切口（I类切口）患者，其中833例（70.35%）患者预防性应用了抗菌药物，351例（29.65%）患者未使用抗菌药物。骨科抗生素预防性应用所占比例最大，占22.69%，其次为胃肠外科，占15.98%，消化内科最少，占1.80%。833例患者使用抗菌药物频次合计1023次，其中头孢硫脒使用频次最高，占31.96%，其次为头孢西丁，占18.08%。抗菌药物的预防性应用随着年份的增加有呈逐渐下降的趋势，但是其应用率仍然较高。大部分患者（69.53%）进行的是抗菌药物的单联用药，二联用药例数占23.53%，三联及以上占6.84%。结论：清洁切口（I类切口）预防性使用抗菌药物出现用药指征把握不严、药物品种选择不当以及抗菌药物疗程不当等问题，因此应加强抗菌药物使用的管理工作。 　　【关键词】清洁切口；围手术期；抗菌药物；预防性应用 　　【中图分类号】R61 【文献标识码】B 【文章编号】1004-6194（2015）01-0080-02 　　【Abstract】Objective：To investigation the prophylactic application situation of antibiotics for clean incision during the perioperative period from 2010 to 2014 in a hospital,to provide the suggestions for rational using antibacterials in clinical.Methods：In total of 1184 data with clean incision in our hospital from 2010 January to 2014 December were retrospective analyzed.The application of antibacterials during the perioperative period was analyzed.Results：In total of 1184 cases with clean incision were investigated,in which 833(70.35%)of patients had prophylactic application of antibacterials when 351(29.65%)of did not use the antibacterials.The department of orthopedics where had prophylactic application of antibacterials for clean incision had the largest proportion,accounted for 22.69%,followed by gastrointestinal surgery(15.93%),the department of internal medicine had the least proportion(1.80%).In total of 1023 times from 833 patients used antibacterials,of which cefathiamidine had the highest frequency(31.96%),followed by cefoxitin(18.08%).It had a trend of gradual decline in prophylactic application of antibacterials increased by the years,but the rate was still high.Most of patients(69.53%)had the single use of antibacterials when 23.53% of two drug jointed.Conclusion：Prophylactic appl