Micromeritics《药剂学》第六章粉体学基础第六节粉体的吸附及粘附第七节粉体的压缩性质 英文PPT.pptxVIP

Micromeritics《药剂学》第六章粉体学基础第六节粉体的吸附及粘附第七节粉体的压缩性质 英文PPT.pptx

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Micromeritics《药剂学》第六章粉体学基础第六节粉体的吸附及粘附

MicrometiticsClass 1 No.4 HeHuan§6 Adhesion cohesiondefinitionAdhesion: Attraction between two unlike surfaces. E.g. between a particle and a hopper wall.Cohesion: Attraction between like surfaces. E.g. component particles of a bulk solid.causesDry condition: Electrostatic forceWet condition: Moisture exists on the surface of the particles to form a liquid bridgeThe particle size Filled discontinuityFlow abilitySo we use Granulation methods to increase the particle size or adding a glident to prevent the adhesion and cohesion.§7 Compression properties of powdersCompression feature representationCompaction:is a general term to describe the situation in which these materials are subjected to some level of mechanical forces.Compression: means a reduction in the bulk volume of the material as a result of displacement of the gaseous phase.Consolation: is an increase in the mechanical strength of the material resulting from particle/particle interactions.Three types of deformationA:elastic deformation: Deformed when pressure is applied, restored when the pressure was released. no binding force.B:Plastic deformation: Deformed when pressure is applied, cannot restored when the pressure was released. Binding force emerge.C: Brittle deformation: particle crushed and deformed under pressure, cannot restored when the pressure was released.Force analysis during the compression processAxial forceRadial forcePoisson ration Usually be 0.4-0.5Relationship between andCoefficient of die-wall friction: Coefficient of lubricant efficiency:frictionLower impulsionThe lubrication efficiency indexUpper impulsionR↑, the better Lubrication efficiency Compression cycle diagramWhen the material is perfectly elastic material compression cycle graph becomes a straight line, the compression process and relieve pressure on the process of change in a straight line.Throughout the compression of the radial force variation with the axial force that can be compression cycle diagram.OA stands for t

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