硫酸镁配伍美托洛尔治疗急性心肌梗死后室性心律失常的效果分析.docVIP

精品论文 参考文献 硫酸镁配伍美托洛尔治疗急性心肌梗死后室性心律失常的效果分析 宜良县第一人民医院 652100 【摘 要】目的：探讨硫酸镁联合美托洛尔治疗急性心肌梗死后室性心律失常的疗效。方法：将74例确诊的患者纳入研究并随机分组，对照组38例采用利多卡因，观察组36例采用硫酸镁联合美托洛尔，比较患者急性心梗后3d内及4至30d内的室性心律失常发生率及治疗前后心功能差异。结果：观察组心梗后3d内及4至30d心梗后室性心律失常发生率均更小，差异显著，Plt;0.05；两组患者治疗后FS、LVEF、E/A均较前升高，但组间比较无显著差异。结论：硫酸镁联合美托洛尔可有效预防急性心肌梗死后室性心律失常发生率，改善心功能，值得推广。 【关键词】硫酸镁；美托洛尔；急性心肌梗死后室性心律失常；效果 [Abstract]：Objective：To investigate the effect of magnesium sulfate combined with metoprolol in the curative effect of ventricular arrhythmia after treatment of acute myocardial infarction. Methods：74 cases of patients into study and randomly divided into two groups，38 patients in the control group were treated with lidocaine，36 cases of observation group were treated with magnesium sulfate combined with metoprolol Er，comparison in patients after acute myocardial infarction within 3 days and 4 to 30 days of ventricular arrhythmia occurrence rate and difference in cardiac function before and after treatment. Results：within 3 days was observed after myocardial infarction group and 4 to 30 days after myocardial infarction ventricular arrhythmia occurrence rate was smaller，significant difference（P lt; 0.05）. Treatment，the patients in the two groups after FS，LVEF，E / a were compared with the previous increased，but between the two groups no significant difference. Conclusion：magnesium sulfate combined with metoprolol can be effective in the prevention of acute myocardial infarction ventricular arrhythmia incidence，improve heart function，worthy of promotion. [Key words]：Magnesium Sulfate；Mei TORO M；ventricular arrhythmias after acute myocardial infarction；effect 急性心肌梗死是指由于冠状动脉粥样硬化、痉挛、炎症等因素长期作用下导致冠状动脉严重狭窄，心肌供血不足的情况下，机体受情绪、寒冷等因素作用下引起的持久胸骨后剧烈疼痛、心律失常、急性循环功能障碍为主要表现的疾病[1]。由于缺血后再灌注伤等因素的影响，不少患者心梗后常可出现心律失常，其中以室性早搏最为多见。临床治疗多选择利多卡因，可取得一定疗效，但作用短暂，心律失常发生率仍较高。我们应用硫酸镁联合美托洛尔治疗，效果显著，在此汇报成果。 1资料与方法 1.1一般资料 均为2013年2月至2015年6月于我院确诊的患者共74例，依据随机数据表法进行分组。对照组中男20例，女18例，年龄63.02plusmn;12.35岁，病程3.72plusmn;2.25h。梗死部位：前壁10