硼替佐米联合地塞米松用于多发性骨髓瘤治疗的临床观察.docVIP

精品论文 参考文献 硼替佐米联合地塞米松用于多发性骨髓瘤治疗的临床观察 赣州市人民医院 江西 赣州 341000 通讯作者：邱帅，36岁，大学本科，赣州人民医院主管护师，主要从事临床护理及消毒供应工作 [摘要]目的：探析硼替佐米联合地塞米松用于多发性骨髓瘤治疗的临床疗效。方法：随机收集2012年1月—2015年12月期间我院诊治的60例多发性骨髓瘤患者，分为对照组与观察组，对照组患者使用吡柔比星、马兰法、长春新碱、地塞米松等药物进行治疗，观察组患者使用硼替佐米联合地塞米松进行治疗，统计分析与比较两组患者的临床治疗效果、肾功能以及不良反应发生率。结果：观察组患者的临床治疗有效率是90%，对照组是66.7%，差异性显著（P＜0.05）。观察组患者的不良反应发生率是53.3%，对照组患者是66.7%，差异性显著（P＜0.05）。观察组患者的肾功能正常率是86.7%，对照组患者是90%，差异性不显著（P＞0.05）。结论：硼替佐米联合地塞米松用于多发性骨髓瘤治疗的临床疗效非常理想，既能够提高患者的临床治疗效果，又不增加患者的不良反应发生率，延长患者的生存期。 关键词：硼替佐米；地塞米松；多发性骨髓瘤；临床治疗效果 【中图分类号】R914.5【文献标识码】A【文章编号】1001-5213(2016)08-0292-01 Boron for Mr M joint dexamethasone for multiple myeloma treatment clinical observation Zhong mingxing Qiu shuai* Ganzhou Peoples Hospital Ganzhou Jiangxi 341000 [abstract] objective: to analysis for boron with m the clinical curative effect of combined therapy with dexamethasone for multiple myeloma. Methods: randomly collected during January 2012 - December 2015, our hospital make a diagnosis and give treatment of 60 cases of patients with multiple myeloma, divided into control group and observation group, control group patients use pyrazole soft than star, Ma Lanfa, vincristine, dexamethasone, such as drug treatment, observation group of patients with m joint treatment with dexamethasone for the use of boron, statistical analysis and comparison of two groups of patients with clinical treatment, renal function and incidence of adverse reactions. Results: the observation group of patients with clinical treatment effectiveness is 90%, the control group was 66.7%, significant difference (P lt; 0.05). Observation group of patients the incidence of adverse reactions was 53.3%, control group patients was 66.7%, significant difference (P lt; 0.05). Observation group of patients with renal ZhengChangLv is 86.7%, the control group patients was 90%, no significant difference (P gt; 0.05). Conclusion: boron for Mr M the clinical curative effect of combined therapy with dexamethasone for multiple myeloma is ideal, b