糖化血红蛋白对2型糖尿病患者C肽和血脂的影响.docVIP

精品论文 参考文献 糖化血红蛋白对2型糖尿病患者C肽和血脂的影响 钱华翔 刘永（常州市第四人民医院 213000） 　　【摘要】目的 探讨糖化血红蛋白对2型糖尿病患者C肽和血脂的影响。方法　54例2型糖尿病患者根据HbA1c水平分为A组（HbA1cle;7.5%）9例，B组（7.5＜HbA1cle;10%）21例，C组（HbA1c＞10%）24例，检验三组间血糖、C肽、TC、TG、HDL、LDL等临床指标的变化。分析HbA1c与这些指标的相关性。结果　（1）C组与A组、B组相比，空腹血糖、餐后血糖、TC、TG水平明显增高（P值lt;0.05）；空腹C肽、餐后C肽水平明显降低（P值lt;0.05）。（2）B组与A组相比，空腹血糖、TC水平明显增高（P值lt;0.05）；餐后C肽水平明显降低（P值lt;0.05）。（3）相关分析表明，HbA1c与空腹血糖、餐后2h血糖、TC、TG呈正相关，与空腹C肽、餐后2hC肽呈负相关（P值lt;0.05）。结论　HbA1c对2型糖尿病患者的C肽、血脂有一定的影响。 　　【关键词】 2型糖尿病 糖化血红蛋白 C肽 血脂 　　【中图分类号】R587.1 【文献标识码】A 【文章编号】2095-1752（2013）32-0117-02 　　HbA1c in patients with type 2 diabetic mellitus C-peptide and lipids effects 　　Qian Hua-xiang, Liu Yong 　　(The Fourth Peoples Hospital of Changzhou, Jiangsu Changzhou 213000) 　　【Abstract】 Objective: To investigate HbA1c in patients with type 2 diabetes C-peptide and lipids. Methods: 54 patients with type 2 diabetes based on HbA1c levels divided into group A (HbA1c le; 7.5%) 9 cases, group B (7.5 lt;HbA1cle;10%)21 cases, group C (HbA1cgt; 10%) 24 cases, three groups glucose, C peptide, TC, TG, HDL, LDL and other clinical indicators of change were detected. Correlation of HbA1c and these indicators was analyzed. Results：(1) Group C compared with group A and group B, fasting blood glucose, postprandial blood glucose, TC, TG levels were significantly higher(Plt;0.05); fasting C-peptide, postprandial C-peptide levels were significantly lower (Plt;0.05). (2) Group B compared with group A, fasting glucose, TC levels were significantly higher (Plt;0.05); postprandial C-peptide levels was significantly lower (P lt;0.05). (3) Correlation analysis showed that, HbA1c and fasting blood glucose, postprandial blood glucose, TC, TG was positive correlation. HbA1c and fasting C-peptide, postprandial C-peptide was negative correlation (P lt;0.05). Conclusion：HbA1c in patients with type 2 diabetes have a certain impact on the levels of C peptide and lipids. 　　【Key words】 Type 2 diabetic mel