缩泉胶囊联合托特罗定片治疗老年女性膀胱过度活动症的效果分析.docVIP

精品论文 参考文献 缩泉胶囊联合托特罗定片治疗老年女性膀胱过度活动症的效果分析 秦 宁 黄 好（通讯作者） 乔子婴 倪凌雁 　　（上海市虹口区江湾镇街道社区卫生服务中心全科 上海 200434) 　　【摘 要】目的：探讨缩泉胶囊联合酒石酸托特罗定片治疗老年女性膀胱过度活动症（Overactive bladder，OAB）的临床疗效，更好地缓解患者症状，提高患者的生活质量。方法：62例均为确诊的OAB患者，均为女性，年龄61-80岁，随机分为实验组32例，即联合治疗组和对照组30例，即托特罗定+安慰剂组。实验组口服缩泉胶囊联合酒石酸托特罗定片；对照组30例，口服安慰剂（淀粉胶囊）加用酒石酸托特罗定片，两组疗程均为4周。结果：实验组治疗，白天排尿次数从（7.53plusmn;0.72）次降为（4.33plusmn;0.69）次；夜间排尿次数从（3.98plusmn;0.58）次降为（2.17plusmn;0.64）次；尿急次数从（4.10plusmn;0.61）次降为（1.64plusmn;0.58）次；尿失禁次数从（10.2plusmn;3.54）降至（8.33plusmn;2.81）。对照组治疗，白天排尿次数从（7.44plusmn;0.71）次降为（5.61plusmn;0.67）次；夜间排尿次数从（4.21plusmn;0.64）次降为（3.55plusmn;0.62）次；尿急次数从（4.23plusmn;0.59）次降为（2.00plusmn;0.58）次；尿失禁次数从（10.55plusmn;4.12）降至（8.65plusmn;3.42）两组间比较，差异有统计学意义（Plt;0.01）。结论：缩泉胶囊与联合酒石酸托特罗定片治疗老年女性膀胱过度活动症较单纯使用酒石酸托特罗定片效果更好，更明显缓解患者症状，提高患者的生活质量，值得在社区推广。 　　【关键词】缩泉胶囊；托特罗定片；膀胱过度活动症；老年女性 　　【中图分类号】R694+.6 【文献标识码】B 【文章编号】1003-5028（2015）5-0039-02 　　【Abstract】Objective：To observe the curative effects of Capsule Suoquan combine with tolterodine tartrate tablets in the treatment of senior female Overactive bladder(OAB). Methods：62 senior female patients were randomized into treatment group(32cases) and control group (30cases).In treatment group, capsule Suoquan was prescribed for oral administration, 6cap./time, 3 times per day, combine with tolterodine tartrate tablet was administrated orally 2mg/time, twice per day. In control group, placebo（capsule starch）was prescribed for oral administration6cap./time, 3 times per day, and tolterodine tartrate tablet was administrated orally 2mg/time, twice per day. The clinical efficacy was observed in two groups for 4 weeks. Results：After 4 weeks, the improvements in urgent urine, frequent urine and urgent urine incontinence were obvious compared with the control group. The total effective in treatment group was superior to that in control group. Conclusion：Capsule Suoquan combine with tolterodine tartrate tablets is more effective than only apply tolterodine tartrate tablets in senior female OAB.