美托洛尔联合螺内酯治疗扩张型心肌病合并心力衰竭疗效观察.docVIP

精品论文 参考文献 美托洛尔联合螺内酯治疗扩张型心肌病合并心力衰竭疗效观察 葛文坤(商丘市第一人民医院心内科 河南商丘 476100) 　　[摘要] 目的:观察美托洛尔联合螺内酯治疗扩张型心肌病合并心力衰竭的疗效。方法:选取2014年10月-2015年12月在我院进行治疗的扩张型心肌病合并心力衰竭患者80例，按治疗方式不同分为两组，各40例。对照组实施常规治疗，研究组实施美托洛尔联合螺内酯治疗，对两组的治疗效果进行观察。结果:研究组患者总有效率（90.0%）较对照组（72.5%）明显升高，差异显著（P＜0.05）。结论:对扩张型心肌病合并心力衰竭患者实施美托洛尔联合螺内酯治疗可有效提高治疗效果，促进患者康复，具有临床使用价值。 　　[关键词] 美托洛尔；螺内酯；扩张型心肌病；合并心力衰竭 　　The curative effect of metoprolol combined with spironolactone in the treatment of patients with heart failure were observed in patients with dilated cardiomyopathy 　　Ge Wenkun (Department of Cardiology, Shangqiu First Peoples Hospital, Shangqiu 476100, Henan) 　　[Abstract] Objective: To observe the curative effect of metoprolol combined with spironolactone in the treatment of dilated cardiomyopathy patients with heart failure. Methods: 80 patients with dilated cardiomyopathy and heart failure treated in our hospital from October 2014 to December -2015 were divided into two groups according to different treatment methods, each of 40 cases. Patients in control group received routine treatment, the study group implementation of spironolactone combined with metoprolol in the treatment, to observe the therapeutic effect of the two groups. Results: the total effective rate of the study group (90%) was significantly higher than that of the control group (72.5%), and the difference was significant (P lt; 0.05). Conclusion: the dilated cardiomyopathy patients with heart failure and implementation of spironolactone combined with metoprolol can effectively improve the therapeutic effect, promote the rehabilitation of patients, it is of clinical value to use. 　　[keyword] metoprolol; spironolactone; dilated cardiomyopathy; heart failure 　　扩张型心肌病是一种常见的原发性心肌疾病，右、左心室或两侧心室同时扩大，心力衰竭是扩张型心肌病患者常见的并发症，严重将导致患者死亡[1-2]。本研究对我院80例患者分别实施常规治疗和美托洛尔联合螺内酯治疗，对两组患者临床疗效进行比较。具体信息如下。 　　1 资料与方法 　　1.1 一般资料 本研究对象为2014年10月-2015年12月在我院进行治疗的扩张型心肌病合并心力衰竭患者80例，所有患者均符合诊断标准。按治疗方式不同分为两组，各40例。对照组：男21例，女19例；年龄41-63岁，平均年龄（49.8plusmn;4.9）岁；病程2-8年，平均病程（4.2plusmn;1.1）年；27例心