慢性肝炎患者血清TBAGLDH水平与肝组织病理炎症分级对比研讨.pdfVIP

慢性肝炎患者血渭TBA,GLDH水平与肝组织 病理炎症分级对比研究 中文摘要 〔目的〕:了解慢性肝炎患者血清TBA,GLDH水平与肝组织炎症程度的关系， 探讨其在评估肝组织炎症程度上的价值。 方〔法〕:对43例慢性肝炎患者进行肝穿刺肝组织病理学检查，同时测定患者 血清TBA,GLDH,ALT,AST,A,TB等生化指标水平。按肝组织病理学检测结 果炎症分级程度将患者分为G1,GGG,组，对不同组间的血清生化指标 结果进行比较。 结〔果〕:慢性肝炎患者肝组织病理分级Gl,GG,期时血清TBA水平分别为 16.58士21.98,20.48士26.13,26.65士28.79,经组间两两比较均无显著差 异，均P0.05,GLDH水平分别为12.75110.58,14.6416.74,28.67141.89 经组间两两比较均无显著差异，均P0.05.ALT水平分别为70.6143.94, 167.82士135.07,161.73士129.21，经组间两两比较有显著性差异，均 P0.05, [结论〕:慢性肝炎患者不同肝组织病理炎症分级之间，血清ALT水平有显著 性差异，血清TBA,GLDH水平则无显著性差异。研究结果提示，血清ALT水 平在一定程度上能较好地反映肝组织炎症程度，而血清TBA,GLDH水平对反 映慢性肝炎肝组织炎症程度方面价值有限。 关〔键ifi:慢性肝炎、肝组织病理学检查、TBA,GDLH,ALT Abstract ComparativeStudyofSerumTBA.GLDHLevelsandPathologic DiagnosisofPatientswithChronicHepatitis Postgraduate:liu jun Tutor: Prof. You jing Aim:ToinvestigatetherelationshipbetweentheserumTBA,GLDHlevelsand theinflammationdegreeoflivertissueofpatientswithchronichepatitis;toprobe theirvalueinevaluationofinflammationdergeeoflivertissue. Method:43patientswithchronichepatitiswereperformedliverpunctureandthe tissueshistologywasstudiedandtheserumoflevelso,TEA,GLDH,ALT, AST,TB,Aweretestedatthesametime.Thepatientsweredividedto4groups accordingtoinflammationdegreeoflivertissue.Theresultsofserumbiochemical testwerecomparedbetweeneachtwogroups. Result:TheserumTEAlevelswere16.98+21.98,20.48+26.13and26.69+28.94 atvariousinflammationdegreeoflivertissue(GI,G2andG3)respectively,and therearenosignificantdifferencebetweeneverytwogroups(PO.均.Theserum GLDH levelswere 12.75+10.98,14.64+6.74and28.67+41.89atvarious inflammationdegreeoflivertissue(GI,G2andG3)respectively,andtherewereno obviouslydifferencebetweeneverytwogroups(PO.OS).TheserumALTlevels were 70.6+43.94,167.82+135.07and161.75+129.21respectively,atvarious inflammationdegreeoflivertissue(GI,G2andG3)respectively