联合检测同型半胱氨酸和缺血修饰白蛋白对急性心肌梗死患者辅助诊断的意义探讨.docVIP

精品论文 参考文献 联合检测同型半胱氨酸和缺血修饰白蛋白对急性心肌梗死患者辅助诊断的意义探讨 李丽 丁良辰 　　（沾化县人民医院检验科 山东滨州 256800） 　　【摘要】目的：分析探讨联合检测同型半胱氨酸和缺血修饰白蛋白对急性心肌梗死患者辅助诊断的意义。方法：选择2013年1月至2015年9月确诊为急性心肌梗死疾病的患者75例设为实验组，选择75例同期进行体检健康者设为对照组，同时检测纳入人群的人血清中的同型半胱氨酸和缺血修饰白蛋白浓度水平，统计分析结果。结果: 实验组的血清同型半胱氨酸和缺血修饰白蛋白浓度水平均明显高于对照组，具有统计学意义的差异（P＜0.05）；实验组患者的同型半胱氨酸和缺血修饰白蛋白的敏感性均超过85%，且两者之间无统计学差异（P＞0.05），联合两项指标检测敏感性明显高于单项检测，均具有统计学意义的差异（P＜0.05），但特异性有所降低。结论：同型半胱氨酸和缺血修饰白蛋白对于辅助诊断急性心肌梗死疾病具有一定的临床意义，联合检测能有效提高敏感性，降低漏诊概率。 　　【关键词】急性心肌梗死；同型半胱氨酸；缺血修饰白蛋白 　　【中图分类号】R446 【文献标识码】A 【文章编号】1007-8231（2015）21-0090-02 　　To explore the clinical significance of the acute myocardial infarction diagnosis by the Homocysteine and Ischemia Modified Albumin joint determination Li Li, Ding Liang-chen. The Laboratory Medicine of the Zhanhua peoplersquo;s hospital , Shandong, China, 256800 　　【Abstract】Objective To explore the clinical significance of the acute myocardial infarction diagnosis by the Homocysteine and Ischemia Modified Albumin joint determination. Methods Choosing 75 cases of patients with the acute myocardial infarction for the experimental group and 70 cases healthy check-up for the control group, testing the plasma Homocysteine and the Ischemia Modified Albumin, analyze the results comprehensively. Results There were significant much Higher of the Homocysteine and the Ischemia Modified Albumin of the experimental group than the control group(P＜0.05). The positive rate of the Homocysteine and the Ischemia Modified Albumin were more than 85%, and there were no significant differences of them(P＞0.05). There were significant much Higher of the Homocysteine and the Ischemia Modified Albumin joint determination than Separate detection(P＜0.05) , but the specificity decreased. Conclusion There both have a certain clinical significance of the Homocysteine and the Ischemia Modified Albumin for the acute myocardial infarction auxiliary diagnosis, and joint detection can improve the sensitivity and reduce the probab